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- W105103463 abstract "The authors have studied several biological systems using laser-polarized {sup 129}Xe. In certain tissues magnetic resonance imaging (MRI) using inhaled laser-polarized noble gases may provide images superior to those from conventional proton MRI. High resolution laser-polarized {sup 3}He images of air spaces in the human lung were recently obtained by the Princeton/Duke group. However, {sup 3}He is not very soluble in tissue. Therefore, the authors are using laser polarized {sup 129}Xe (tissue-soluble), with the long term goal of biomedical functional imaging. They have investigated multi-echo and multi-excitation magnetic resonance detection schemes to exploit the highly non-thermal {sup 129}Xe magnetization produced by the laser polarization technique. They have inhalated live rats with laser-polarized {sup 129}Xe gas and measured three distinct {sup 129}Xe tissue resonances that last 20 to 40 sec. As a demonstration, the authors obtained a laser polarized {sup 129}Xe image of the human oral cavity. Currently they are measuring and polarization lifetime of {sup 129}Xe dissolved in human blood, the biological transporting medium. These studies are other recent developments will be reported." @default.
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- W105103463 date "1996-05-01" @default.
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- W105103463 title "Biological studies with laser-polarized" @default.
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