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- W105306089 abstract "This chapter describes the antioxidant activity of dietary flavonoids, especially quercetin and (-)-epicatechin, from the standpoint of antioxidant defense on lipid peroxidation in blood plasma and plasma lipoproteins. Polyphenolic flavonoids can exert inhibitory effects on lipid peroxidation by scavenging chain-initiating oxygen radicals as well as chain-propagating lipid peroxyl radicals. Because of their physical properties, flavonoids seem to be localized near the interface between the lipid phase and the water phase in heterogeneous biological systems. However, the efficiency of intestinal absorption and following metabolic conversion should be taken into account for the estimation of in vivo activity. It is suggested that flavonoids are already subjected to glucuronyl conjugation in the intestinal mucosa during absorption. Some conjugates containing a free phenolic group are likely to possess antioxidant activity to some extent in blood circulation. In particular, dietary flavonoids are expected to help in the prevention of coronary heart disease, as epidemiological studies have shown the inverse relationship between the intake of dietary flavonoids and coronary heart disease." @default.
- W105306089 created "2016-06-24" @default.
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- W105306089 date "1999-01-01" @default.
- W105306089 modified "2023-10-15" @default.
- W105306089 title "Dietary Flavonoids as Plasma Antioxidants on Lipid Peroxidation" @default.
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- W105306089 doi "https://doi.org/10.1016/b978-012543590-1/50018-4" @default.
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