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- W105476645 endingPage "40" @default.
- W105476645 startingPage "25" @default.
- W105476645 abstract "B cells provide a variety of important functions to the adaptive immune system including antibody production, antigen presentation, and cytokine secretion, as well as being required for the development of proper lymphoid architecture. B cells originate in the bone marrow, where they mature and produce an initial diverse repertoire of non-self reactive B-cell receptors. After moving to the periphery, naïve B cells are presented with antigen by dendritic and other antigen-presenting cells. B cells that come in contact with and can recognize antigen become activated, expand, and further alter the B-cell receptor to improve antigen specificity through somatic hypermutation and affinity maturation. This B-cell receptor is subsequently secreted as active, mature antibody. Antibodies are able to recognize and bind to bacteria, viruses, and other antigens, initiating a cascade of processes that rid the body of pathogens." @default.
- W105476645 created "2016-06-24" @default.
- W105476645 creator A5020071542 @default.
- W105476645 creator A5026504972 @default.
- W105476645 date "2013-01-01" @default.
- W105476645 modified "2023-09-25" @default.
- W105476645 title "Adaptive Immunity" @default.
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