Matches in SemOpenAlex for { <https://semopenalex.org/work/W105759098> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W105759098 endingPage "95" @default.
- W105759098 startingPage "87" @default.
- W105759098 abstract "Acquisition of repertoires and genetic restriction specificities of suppressor T cells (Ts) and their factors were studied by using full allogeneic radiation bone marrow chimera and H-2 congenic pairs, B10.A(3R) and B10.A(5R), which received conventional or cloned macrophages by cell transfer. Suppressor T-cell factor (TsF) from C3H----C57BL/6 or C57BL/6----C3H chimera suppressed only donor but not host-type responses of either C3H or C57BL/6, in an antigen-specific fashion. However, if chimera mice were given conventional or cloned macrophages of the host type, the chimera TsF in turn suppressed both the responses of C3H and C57BL/6 mice but not those of the third party, BALB/c, indicating that macrophages are responsible for the acquisition of host restriction specificity. Similarly, B10.A(5R) mice developed I-Jb restricted Ts or TsF when the B10.A(3R) macrophage cell line was injected at the time of antigen priming. The reverse was also true. B10.A(3R) mice did generate I-Jk restricted Ts when they received the B10.A(5R) macrophage cell line. Thus, the results clearly demonstrated that B10.A(3R) or B10.A(5R) mice potentially possessed their ability to express both I-Jk and I-Jb determinants and that repertoires and genetic restriction specificity of Ts and their TsF were acquired at a macrophage level at the time of antigen-priming." @default.
- W105759098 created "2016-06-24" @default.
- W105759098 creator A5017060166 @default.
- W105759098 creator A5017653338 @default.
- W105759098 creator A5035894578 @default.
- W105759098 creator A5083776612 @default.
- W105759098 date "1988-01-01" @default.
- W105759098 modified "2023-09-27" @default.
- W105759098 title "Acquisition of repertoires of suppressor T cells under the influence of macrophages." @default.
- W105759098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2855588" @default.
- W105759098 hasPublicationYear "1988" @default.
- W105759098 type Work @default.
- W105759098 sameAs 105759098 @default.
- W105759098 citedByCount "0" @default.
- W105759098 crossrefType "journal-article" @default.
- W105759098 hasAuthorship W105759098A5017060166 @default.
- W105759098 hasAuthorship W105759098A5017653338 @default.
- W105759098 hasAuthorship W105759098A5035894578 @default.
- W105759098 hasAuthorship W105759098A5083776612 @default.
- W105759098 hasConcept C100701293 @default.
- W105759098 hasConcept C104317684 @default.
- W105759098 hasConcept C147483822 @default.
- W105759098 hasConcept C153911025 @default.
- W105759098 hasConcept C179185449 @default.
- W105759098 hasConcept C203014093 @default.
- W105759098 hasConcept C2776090121 @default.
- W105759098 hasConcept C30278631 @default.
- W105759098 hasConcept C54355233 @default.
- W105759098 hasConcept C59822182 @default.
- W105759098 hasConcept C81444415 @default.
- W105759098 hasConcept C84951073 @default.
- W105759098 hasConcept C86803240 @default.
- W105759098 hasConcept C8891405 @default.
- W105759098 hasConceptScore W105759098C100701293 @default.
- W105759098 hasConceptScore W105759098C104317684 @default.
- W105759098 hasConceptScore W105759098C147483822 @default.
- W105759098 hasConceptScore W105759098C153911025 @default.
- W105759098 hasConceptScore W105759098C179185449 @default.
- W105759098 hasConceptScore W105759098C203014093 @default.
- W105759098 hasConceptScore W105759098C2776090121 @default.
- W105759098 hasConceptScore W105759098C30278631 @default.
- W105759098 hasConceptScore W105759098C54355233 @default.
- W105759098 hasConceptScore W105759098C59822182 @default.
- W105759098 hasConceptScore W105759098C81444415 @default.
- W105759098 hasConceptScore W105759098C84951073 @default.
- W105759098 hasConceptScore W105759098C86803240 @default.
- W105759098 hasConceptScore W105759098C8891405 @default.
- W105759098 hasIssue "2" @default.
- W105759098 hasLocation W1057590981 @default.
- W105759098 hasOpenAccess W105759098 @default.
- W105759098 hasPrimaryLocation W1057590981 @default.
- W105759098 hasRelatedWork W105759098 @default.
- W105759098 hasRelatedWork W1570475424 @default.
- W105759098 hasRelatedWork W1583487173 @default.
- W105759098 hasRelatedWork W2031508422 @default.
- W105759098 hasRelatedWork W2033998433 @default.
- W105759098 hasRelatedWork W2065278508 @default.
- W105759098 hasRelatedWork W2129235755 @default.
- W105759098 hasRelatedWork W2156222046 @default.
- W105759098 hasRelatedWork W2415730858 @default.
- W105759098 hasRelatedWork W2483178925 @default.
- W105759098 hasVolume "4" @default.
- W105759098 isParatext "false" @default.
- W105759098 isRetracted "false" @default.
- W105759098 magId "105759098" @default.
- W105759098 workType "article" @default.