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• W1060041493 abstract "In this study, the genetic variability of Chinese indigenous goat breeds (Capra hircus) was analyzed using the MHC-associated microsatellite markers BF1, BM1818, BM1258, and DYMS1. To examine genetic variability, the levels of heterozigosity, degrees of inbreeding, and genetic differences among the breeds were analyzed. The mean number of alleles ranged from 5.50 ± 3.70 in Enshi black goats (EB) to 11.50 ± 3.70 in the Jianyang big ear (JE) breed. The mean observed heterozygosity and mean expected heterozygosity varied from 0.25 ± 0.04 in Jining Qing goats (JQ) to 0.54 ± 0.05 in Chuannan black goats (CN) and from 0.49 ± 0.18 in Hechuan white goats (HW) to 0.78 ± 0.05 in JE, respectively. The mean FIS values ranged from 0.23 in HW to 0.51 in JQ. In addition, the genetic variation among populations and geographic location did indicate a correlation of genetic differences with geographic distance, which was revealed by the phylogenetic network. In conclusion, the high variability and population structure among Chinese native goats in the Major Histocompatibility Complex would be caused by co-evolution between MHC alleles and the epidemic history or pathogens in different agro-ecological zones." @default.
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• W1060041493 date "2015-10-01" @default.
• W1060041493 modified "2023-10-17" @default.
• W1060041493 title "Genetic variability of ten Chinese indigenous goats using MHC-linked microsatellite markers" @default.
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• W1060041493 doi "https://doi.org/10.1016/j.vetimm.2015.07.013" @default.
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