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- W107344825 abstract "Alzheimer's disease is the most common cause of dementia in the elderly. Several potential factors have been described, which may determine the risk for the development of Alzheimer's disease. Among these, genetic factorsplay the most important role. From a genetic point of view, Alzheimer's disease may be subdivided into three forms according to the observed mode of inheritance: autosomal-dominant familial Alzheimer's disease, familial Alzheimer's disease without clear Mendelian inheritance (i.e. familial aggregation), and sporadic Alzheimer's disease without familial aggregation. This review article gives an overview of genetic research strategies in Alzheimer's disease, describes the known mutations resulting in an autosomal-dominant pattern of inheritance, and discusses some commonly accepted genetic susceptibility factors associated with the more common forms of Alzheimer's disease." @default.
- W107344825 created "2016-06-24" @default.
- W107344825 date "2001-12-05" @default.
- W107344825 modified "2023-10-17" @default.
- W107344825 title "Genetics of Alzheimer's disease" @default.
- W107344825 doi "https://doi.org/10.4414/sanp.2001.01243" @default.
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