FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W107366525> ?p ?o ?g. }

• W107366525 abstract "OF DISSERTATION THE INFLUENCE OF SELENIUM STATUS ON IMMUNE FUNCTION AND ANTIOXIDANT STATUS IN THE HORSE Selenium (Se) has received a lot of attention for its antioxidant and immune modulating properties. Yet, comparably few studies have focused on the horse. Therefore the objectives of this research were to evaluate the influences of Se status on immune function and antioxidant defense in horses. Twenty eight horses were allocated to one of 4 dietary Se treatments: low (LS), adequate (AS), high organic (SP) and high inorganic (SS). First, horses assigned to LS, SP and SS were depleted of Se and received a low Se diet (0.07 ppm Se) for 35 wk, while AS received an adequate Se diet (0.14 ppm Se). During week 28 to 35 immune function was evaluated using a vaccine challenge with keyhole limpet hemocyanin (KLH) and equine influenza as antigens. Then, a 29 wk repletion phase followed. The LS and AS received the same diets described above while SP received an organic Se supplemented diet (0.3 ppm; Sel-Plex, Alltech, Nicholasville, KY) and SS an inorganic Se supplemented diet (0.3 ppm; sodium selenite). Immune function was assessed using a vaccine challenge with ovalbumin (OVA) and equine influenza as antigens during week 22 to 29. Samples collected throughout the depletion and repletion phases were used to assess change in Se status, antioxidant status and oxidative stress. Finally, a mild exercise test served to assess exercise induced oxidative stress. The experimental model responded as hypothesized, evaluated by blood Se and glutathione peroxidase (GPx) activity. Upon vaccination with KLH, antibody response was faster in AS than LS. Antigen specific mRNA expression of T-bet was also higher for AS than LS. Following OVA vaccination humoral and cell-mediated vaccination responses were similar across treatments. However, non-specific stimulation of peripheral blood mononuclear cells indicated suppressed mRNA expression of selected cytokines for LS compared to AS, SP and SS. Antioxidant capacity and oxidative stress were unaffected by change in Se status. A difference in GPx response post exercise was also noted between SP and SS. Low Se status impaired some measures of immune function. Supplementation at 0.3 ppm may benefit horses as indicated by higher GPx activity in idle and exercised horses." @default.
• W107366525 created "2016-06-24" @default.
• W107366525 creator A5082742995 @default.
• W107366525 date "2012-01-01" @default.
• W107366525 modified "2023-09-26" @default.
• W107366525 title "THE INFLUENCE OF SELENIUM STATUS ON IMMUNE FUNCTION AND ANTIOXIDANT STATUS IN THE HORSE" @default.
• W107366525 cites W1505402127 @default.
• W107366525 cites W1515410606 @default.
• W107366525 cites W1584742655 @default.
• W107366525 cites W1687035583 @default.
• W107366525 cites W1700381808 @default.
• W107366525 cites W1886258150 @default.
• W107366525 cites W1906541547 @default.
• W107366525 cites W1907301733 @default.
• W107366525 cites W1907661381 @default.
• W107366525 cites W1923677633 @default.
• W107366525 cites W1960984556 @default.
• W107366525 cites W1971062441 @default.
• W107366525 cites W1976323290 @default.
• W107366525 cites W1978370917 @default.
• W107366525 cites W1980220254 @default.
• W107366525 cites W1980671568 @default.
• W107366525 cites W1982180091 @default.
• W107366525 cites W1982520928 @default.
• W107366525 cites W1982907329 @default.
• W107366525 cites W1991724656 @default.
• W107366525 cites W1992914112 @default.
• W107366525 cites W1993098161 @default.
• W107366525 cites W1993339884 @default.
• W107366525 cites W1993938650 @default.
• W107366525 cites W1995744610 @default.
• W107366525 cites W1995858428 @default.
• W107366525 cites W1997001210 @default.
• W107366525 cites W2001116625 @default.
• W107366525 cites W2002298472 @default.
• W107366525 cites W2004805241 @default.
• W107366525 cites W2006313098 @default.
• W107366525 cites W2007887382 @default.
• W107366525 cites W2009438727 @default.
• W107366525 cites W2009663398 @default.
• W107366525 cites W2009774485 @default.
• W107366525 cites W2012401983 @default.
• W107366525 cites W2012989928 @default.
• W107366525 cites W2014721145 @default.
• W107366525 cites W2017096006 @default.
• W107366525 cites W2017392037 @default.
• W107366525 cites W2021051803 @default.
• W107366525 cites W2022675149 @default.
• W107366525 cites W2027064670 @default.
• W107366525 cites W2027581129 @default.
• W107366525 cites W2028687970 @default.
• W107366525 cites W2031911490 @default.
• W107366525 cites W2041382001 @default.
• W107366525 cites W2042201172 @default.
• W107366525 cites W2050183208 @default.
• W107366525 cites W2050239922 @default.
• W107366525 cites W2050782694 @default.
• W107366525 cites W2052819301 @default.
• W107366525 cites W2053220031 @default.
• W107366525 cites W2054841888 @default.
• W107366525 cites W2055902416 @default.
• W107366525 cites W2055973186 @default.
• W107366525 cites W2056135446 @default.
• W107366525 cites W2060555072 @default.
• W107366525 cites W2063151468 @default.
• W107366525 cites W2067578768 @default.
• W107366525 cites W2068621717 @default.
• W107366525 cites W2069523516 @default.
• W107366525 cites W2072440272 @default.
• W107366525 cites W2075823048 @default.
• W107366525 cites W2077616783 @default.
• W107366525 cites W2078455372 @default.
• W107366525 cites W2082676436 @default.
• W107366525 cites W2084369543 @default.
• W107366525 cites W2084379054 @default.
• W107366525 cites W2086020105 @default.
• W107366525 cites W2094068172 @default.
• W107366525 cites W2096387617 @default.
• W107366525 cites W2098546641 @default.
• W107366525 cites W2099316303 @default.
• W107366525 cites W2101518804 @default.
• W107366525 cites W2102299555 @default.
• W107366525 cites W2106398147 @default.
• W107366525 cites W2107277218 @default.
• W107366525 cites W2107521540 @default.
• W107366525 cites W2107741385 @default.
• W107366525 cites W2109779069 @default.
• W107366525 cites W2111555939 @default.
• W107366525 cites W2111577111 @default.
• W107366525 cites W2112516644 @default.
• W107366525 cites W2115244008 @default.
• W107366525 cites W2116186771 @default.
• W107366525 cites W2116885745 @default.
• W107366525 cites W2117874346 @default.
• W107366525 cites W2118611619 @default.
• W107366525 cites W2118728677 @default.
• W107366525 cites W2118745476 @default.
• W107366525 cites W2119906602 @default.
• W107366525 cites W2120222399 @default.
• W107366525 cites W2123704697 @default.

• next