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- W107788573 abstract "The kidney contains for basic components: blood, intercellular space, tissue, and urine. Blood and urine are transients. Blood enters and leaves the organ, while urine is being formed and continuously modified when leaving the kidney in the direction of the renal pelvis. The tissue, and to a certain extent the extracellular space, is comparatively stationary. The tissue confines urine once it has been formed by glomerular filtration, blood, and the extracellular space to separate compartments and builds channel systems for urine, blood, and extracellular fluid. This tissue “framework” also ensures adequate conditions for the interrelationship between urine and blood which is modulated by the fourth compartment, the extracellular space. The close relationship between vasculature and the uriniferous system can be appreciated by studying the development of the kidney. During embryonal development three bilateral excretory systems are formed from the nephrogenic cord, the pronephros, the mesonephros, and the metanephros. While the pronephros and mesonephros undergo regression, the metanephros forms the final kidney. There exist two regions from which the organ formation starts: the nephrogenic ridge and a specialized structure of the mesonephric duct called the ureteric bud. The ureteric bud grows cranially and contacts the nephrogenic ridge from which renal corpuscles and tubules start to develop. The renal vasculature, on the other hand, is assumed to develop in situ by first forming sinusoid-like structures intermingled between the nephrons spreading out from the condensed mesenchyme, which is located close to the ampullae of the ureteric bud.KeywordsProximal TubuleDistal TubuleDistal NephronOuter MedullaNephron SegmentThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
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- W107788573 date "1982-01-01" @default.
- W107788573 modified "2023-10-16" @default.
- W107788573 title "Organization of the Rat Kidney" @default.
- W107788573 doi "https://doi.org/10.1007/978-3-642-68287-2_2" @default.
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