FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W107893399> ?p ?o ?g. }

• W107893399 endingPage "798" @default.
• W107893399 startingPage "793" @default.
• W107893399 abstract "Colchicine injection was used as a tool to potentiate the increase in intracellular lipoprotein lipase (type L hormone-sensitive lipase) activity normally seen with fasting to determine if elevation of enzyme activity by this method produced a reduction in endogenous triacylglycerol (TG) in rat heart. Both fasting and fasting+colchicine treatment increased total lipoprotein lipase (LPL) activity from a control value of 80 units/g to approx. 144 units/g. The initial control value was obtained at 08:00 h after overnight feeding and the final values were obtained at 17:00 h, after 9 h of fasting. Fasting alone increased activity in both the capillary-bound LPL and type L hormone-sensitive lipase (HSL) fractions of cardiac muscle. In contrast, colchicine treatment, by blocking the export of enzyme from the cell as a result of microtubular disruption, restricted the increase in enzyme activity to the intracellular fraction of the heart. There was a highly significant (P less than 0.001) negative relationship (r = −0.73) between type L HSL activity and TG content in hearts of fasting and fasting+colchicine-treated rats. At a time when type L HSL activity was increased and TG content decreased, the cyclic AMP concentration of heart remained unchanged, ruling out the possibility that cyclic AMP might be activating any one of the identified cardiac TG lipases. These data provided indirect evidence that type L HSL is ‘seeing the intracellular TG droplet’ and that this enzyme may play a role in the regulation of myocardial lipolysis." @default.
• W107893399 created "2016-06-24" @default.
• W107893399 creator A5043050710 @default.
• W107893399 creator A5049580118 @default.
• W107893399 creator A5069678967 @default.
• W107893399 date "1984-12-15" @default.
• W107893399 modified "2023-10-17" @default.
• W107893399 title "Relationship between type L hormone-sensitive lipase activity and endogenous triacylglycerol in the hearts of colchicine-treated rats" @default.
• W107893399 cites W1490801702 @default.
• W107893399 cites W1728792 @default.
• W107893399 cites W1963611164 @default.
• W107893399 cites W1974856290 @default.
• W107893399 cites W1991606219 @default.
• W107893399 cites W1991834931 @default.
• W107893399 cites W1995973712 @default.
• W107893399 cites W2004717108 @default.
• W107893399 cites W2005697969 @default.
• W107893399 cites W2008190738 @default.
• W107893399 cites W2020114335 @default.
• W107893399 cites W2026727806 @default.
• W107893399 cites W2027720676 @default.
• W107893399 cites W2027728858 @default.
• W107893399 cites W2031988638 @default.
• W107893399 cites W2034562003 @default.
• W107893399 cites W2041802340 @default.
• W107893399 cites W2050452563 @default.
• W107893399 cites W2055766215 @default.
• W107893399 cites W2055789770 @default.
• W107893399 cites W2057810798 @default.
• W107893399 cites W2064122000 @default.
• W107893399 cites W2072608915 @default.
• W107893399 cites W2089250699 @default.
• W107893399 cites W2094168708 @default.
• W107893399 cites W2094283571 @default.
• W107893399 cites W2104024744 @default.
• W107893399 cites W2235434683 @default.
• W107893399 cites W2280133629 @default.
• W107893399 cites W2328990604 @default.
• W107893399 cites W2331765640 @default.
• W107893399 cites W2335788947 @default.
• W107893399 cites W2345021934 @default.
• W107893399 cites W2407311363 @default.
• W107893399 cites W2417065058 @default.
• W107893399 cites W2417625781 @default.
• W107893399 cites W2418051006 @default.
• W107893399 cites W2462976407 @default.
• W107893399 cites W2467447252 @default.
• W107893399 cites W2467490660 @default.
• W107893399 cites W4289952861 @default.
• W107893399 doi "https://doi.org/10.1042/bj2240793" @default.
• W107893399 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1144515" @default.
• W107893399 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6098267" @default.
• W107893399 hasPublicationYear "1984" @default.
• W107893399 type Work @default.
• W107893399 sameAs 107893399 @default.
• W107893399 citedByCount "5" @default.
• W107893399 crossrefType "journal-article" @default.
• W107893399 hasAuthorship W107893399A5043050710 @default.
• W107893399 hasAuthorship W107893399A5049580118 @default.
• W107893399 hasAuthorship W107893399A5069678967 @default.
• W107893399 hasBestOaLocation W1078933992 @default.
• W107893399 hasConcept C126322002 @default.
• W107893399 hasConcept C134018914 @default.
• W107893399 hasConcept C140985366 @default.
• W107893399 hasConcept C16613235 @default.
• W107893399 hasConcept C171089720 @default.
• W107893399 hasConcept C181199279 @default.
• W107893399 hasConcept C185592680 @default.
• W107893399 hasConcept C2776636253 @default.
• W107893399 hasConcept C2778500429 @default.
• W107893399 hasConcept C2779697368 @default.
• W107893399 hasConcept C2781227529 @default.
• W107893399 hasConcept C28212737 @default.
• W107893399 hasConcept C55493867 @default.
• W107893399 hasConcept C71315377 @default.
• W107893399 hasConcept C71924100 @default.
• W107893399 hasConcept C79879829 @default.
• W107893399 hasConcept C86803240 @default.
• W107893399 hasConcept C94879076 @default.
• W107893399 hasConceptScore W107893399C126322002 @default.
• W107893399 hasConceptScore W107893399C134018914 @default.
• W107893399 hasConceptScore W107893399C140985366 @default.
• W107893399 hasConceptScore W107893399C16613235 @default.
• W107893399 hasConceptScore W107893399C171089720 @default.
• W107893399 hasConceptScore W107893399C181199279 @default.
• W107893399 hasConceptScore W107893399C185592680 @default.
• W107893399 hasConceptScore W107893399C2776636253 @default.
• W107893399 hasConceptScore W107893399C2778500429 @default.
• W107893399 hasConceptScore W107893399C2779697368 @default.
• W107893399 hasConceptScore W107893399C2781227529 @default.
• W107893399 hasConceptScore W107893399C28212737 @default.
• W107893399 hasConceptScore W107893399C55493867 @default.
• W107893399 hasConceptScore W107893399C71315377 @default.
• W107893399 hasConceptScore W107893399C71924100 @default.
• W107893399 hasConceptScore W107893399C79879829 @default.
• W107893399 hasConceptScore W107893399C86803240 @default.
• W107893399 hasConceptScore W107893399C94879076 @default.
• W107893399 hasIssue "3" @default.

• next