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- W108248014 abstract "In the dexamethasone suppression test (DST), the potent synthetic adrenal steroid hormone dexamethasone is used to test the drive by higher brain centers as well as the intrinsic autonomous activity of the hypothalamic-pituitary-adrenal cortical (HPA) axis. Dexamethasone acts primarily at the pituitary gland to suppress the secretion of adrenocorticotropic hormone (ACTH), which, in turn, suppresses the secretion of hormones from the adrenal cortex. Under normal conditions, this suppression is complete and relatively long-lasting. However, when there is abnormal driving of the HPA axis by the brain or intrinsic pathology within the HPA axis leading to hyperactivity, the suppressive effect of dexamethasone is weaker and of shorter duration. Depending on the degree of nonsuppression, certain abnormal processes may be suspected and/or confirmed." @default.
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- W108248014 date "2007-01-01" @default.
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- W108248014 title "Dexamethasone Suppression Test (DST)" @default.
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- W108248014 doi "https://doi.org/10.1016/b978-012373947-6.00120-3" @default.
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