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- W108380863 abstract "This chapter reviews the subject of natural antibodies by analyzing the experimental data that demonstrate their existence and characteristics in both invertebrates and vertebrates. Their actions are related to those of other serum constituents that also participate in the serological recognition of foreign substances. The still unanswered questions of the origin of natural antibodies and their possible role in the recognition of antigens and in the initiation of the immune response are discussed in the chapter. The question proposed in the chapter is whether the postulated recognition factors of the immune system are detectable in serum or are attached to certain cells as natural antibodies. The available data is not sufficient to allow an answer to this question, it nevertheless seems of interest to discuss to what extent these data are compatible with the notion that some natural antibodies may represent the recognition factors of acquired immunity. The chapter also discusses the occurrence, origin, and characteristics (specificity and avidity, heat stability, electrophoretic properties, and molecular weight) of the natural antibodies." @default.
- W108380863 created "2016-06-24" @default.
- W108380863 creator A5086309123 @default.
- W108380863 date "1966-01-01" @default.
- W108380863 modified "2023-10-17" @default.
- W108380863 title "Natural Antibodies and the Immune Response" @default.
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- W108380863 doi "https://doi.org/10.1016/s0065-2776(08)60271-0" @default.
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