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- W109054394 abstract "This chapter discusses the sensitivity to lipid solvent. Enveloped viruses are usually susceptible to the action of lipid solvents, such as ether or chloroform. Exposure to these solvents results in a marked decrease in virus infectivity. Non-enveloped viruses do not exhibit such a decrease in infectivity when treated similarly. Ether and chloroform fragment the cell membrane that envelops the virus and expose the nucleic acid and protein core. A given virus is considered sensitive if exposure to the lipid solvent results in a 1 log decrease in infectivity as compared to unexposed controls. The chapter presents an experiment where EMC virus and NDV are exposed to chloroform for 10 minutes at room temperature and titrated. Any infectious assay may be used to determine the titer of these samples following their exposure to the lipid solvent." @default.
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- W109054394 date "1992-01-01" @default.
- W109054394 modified "2023-09-26" @default.
- W109054394 title "SENSITIVITY TO LIPID SOLVENTS" @default.
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- W109054394 doi "https://doi.org/10.1016/b978-0-12-144730-4.50027-8" @default.
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