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• W109906818 abstract "A novel optical method of guiding epidural catheter insertion is introduced due to high failure rate of traditional technique for epidural blocks. Experiments of ex-vivo and in-vivo in porcine were performed. In the ex-vivo study the optically reflective spectra of identified porcine tissues were obtained. By which wavelengths of 650 nm and 532 nm were selected to differentiate epidural space and ligamentum flavum (LF). A specially designed hollow stylet that contained optical fibers served for tissue illumination and receiving reflected light from tissue in the in-vivo experiment. The data was real-time displayed on an oscilloscope and stored for analysis. A total of 50 punctures were done in four 20-kg pigs. Two-way ANOVA for reflective lights of 650 and 532 nm indicates no significant difference at the different puncture sites for LF and epidural space (all p>0.05). Mean magnitudes for 650 nm and 532 nm and their ratio at epidural space and LF were 3.565+/-0.194, 2.542+/-0.145, 0.958+/-0.172 and 3.842+/-0.191, 2.563+/-0.131, 1.228+/-0.244 respectively. Paired t test showed that significant differences occurred between epidural spaces and LF in both 650nm (p<0.001), 532nm (p=0.014) and their ratio (p <0.001). Verification using receiver operating characteristic for the three tests with 95% confidence interval indicates the area under curve for lights of 650 nm, 532 nm and their ratio were about 0.887, 0.549 and 0.809 respectively. Optical feature extraction is the core technique in this study to distinguish different in-vivo tissues so that the epidural space can be localized on the spot without additional guiding assistance in a porcine model." @default.
• W109906818 created "2016-06-24" @default.
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• W109906818 date "2012-07-24" @default.
• W109906818 modified "2023-09-24" @default.
• W109906818 title "A novel optical method of guiding epidural catheter placement for epidural block" @default.
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