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- W110702935 abstract "The thymus-derived system is under the regulation of a variety of exogenous and endogenous mediators. Mediators of the autonomic nervous system, the “classic” endocrine system, and the thymic endocrine system act in concert with endogenous lymphokines, prostaglandins, eicosanoids, and inflammatory molecules to regulate the system. The former can be envisioned to provide the molecular “background” for development of the system and the maintenance of the functional integrity of the system. The latter signals derive from its activation in response to antigenic stimuli and, therefore, more likely qualify as “acute phase” regulators signaling abrupt changes in direction. Recent advances in understanding the mechanisms of transmembrane signal transmission including phospholipid methylation, PI turnover, AA release, Ca2+ influx, protein kinases (c, cAMP, and cGMP) cyclic nucleotide cyclases, ATPases, etc. offer a wealth of opportunity to study the mechanisms involved in neuroimmunomodulation." @default.
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- W110702935 date "1986-01-01" @default.
- W110702935 modified "2023-10-18" @default.
- W110702935 title "Transmembrane Signaling Mechanisms in Neuroendocrine Modulation of the Thymus-Dependent Immune System" @default.
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- W110702935 doi "https://doi.org/10.1016/b978-0-12-174685-8.50061-5" @default.
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