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- W110834013 abstract "-chymotrypsin were fabricated by sequential adsorption technique. Protein aggregates preparedby salting out were consecutively treated by oppositely charged polyelectrolytes to yield polyelectrolyte microparticles contai ning protein. Majorcharacteristics of microparticles such as incorporation efficiency and protein content were strongly dependent on the number of polyelectrolytetreatments. Polyelectrolyte microparticles were found to be pH-sensitive as they can release embedded protein at certain condit ions and can alsouptake the protein from its surrounding medium. The possibility to control the protein release by altering the manufacturing co nditions and pH ofthe medium was demonstrated.Key words: Protein encapsulation – Microparticles – Controlled release – Polyelectrolytes – Consecutive adsorption – Protein aggregates." @default.
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- W110834013 date "2003-01-01" @default.
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- W110834013 title "Model system for controlled protein release: pH-sensitive polyelectrolyte microparticles" @default.
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