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- W111241138 abstract "Cystathionine beta-synthase and gamma-cystathionase, the two major enzymes of the transsulfuration pathway of methionine metabolism, are described. These enzymes are responsible for inborn errors, e.g., homocystinuria and cystathioninuria. The interaction of gamma-cystathionase with the cofactor, substrates and inhibitors of the general formula RONH2 containing structural fragments of substrates has been studied. A non-radioactive avidin-biotin system for the microdetection of gamma-cystathionase in dot blots has been developed. This system was applied for immunoscreening of a rat liver cDNA library in the prokaryotic expression vector lambda gt 11." @default.
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- W111241138 date "1989-05-01" @default.
- W111241138 modified "2023-09-23" @default.
- W111241138 title "[Pyridoxal phosphate-dependent enzymes of sulfur amino acid metabolism]." @default.
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