Matches in SemOpenAlex for { <https://semopenalex.org/work/W1122588891> ?p ?o ?g. }
- W1122588891 endingPage "83" @default.
- W1122588891 startingPage "52" @default.
- W1122588891 abstract "Human influenza virus was first isolated and identified in the United Kingdom in 1933. The prerequisites for the work on the influenza virus were the discovery of a vital protein of the virus, hemagglutinin (HA); identification of the hemagglutinating ability of the influenza virus in chicken and mammalian erythrocytes; and, most importantly, discovery of the hemagglutination inhibition (HI) test. This chapter focuses on the HA protein of the influenza A virus. The first serological study in animal models and postinfection human sera indicated a surprising degree of antigenic change or drift of the HA. It was the emergence of a completely novel influenza A virus in Asia in 1957 and another in 1968 that confirmed the suspicion—harbored since the Great Spanish Pandemic of 1918—that the influenza A virus had two epidemiological faces or modes, epidemic and pandemic. With the advent of new techniques of protein chemistry and electron microscopy, it has become clear that the HA is the most important antigen of the virus and is made up of two polypeptides—HA1 and HA2. These two constituents of the HA were separated and studied by peptide mapping, and it was discovered that antigenic changes occur entirely in HAl molecules." @default.
- W1122588891 created "2016-06-24" @default.
- W1122588891 creator A5005207519 @default.
- W1122588891 creator A5016309968 @default.
- W1122588891 creator A5060275560 @default.
- W1122588891 creator A5060459635 @default.
- W1122588891 date "2003-01-01" @default.
- W1122588891 modified "2023-09-26" @default.
- W1122588891 title "Influenza — The Chameleon Virus" @default.
- W1122588891 cites W1483301458 @default.
- W1122588891 cites W1485948130 @default.
- W1122588891 cites W1540149725 @default.
- W1122588891 cites W1576782716 @default.
- W1122588891 cites W1598417225 @default.
- W1122588891 cites W1938736800 @default.
- W1122588891 cites W19635477 @default.
- W1122588891 cites W1967579117 @default.
- W1122588891 cites W1977527856 @default.
- W1122588891 cites W1978763290 @default.
- W1122588891 cites W1979537384 @default.
- W1122588891 cites W1981316697 @default.
- W1122588891 cites W1984412128 @default.
- W1122588891 cites W1984416131 @default.
- W1122588891 cites W1990393481 @default.
- W1122588891 cites W1990428998 @default.
- W1122588891 cites W1998977072 @default.
- W1122588891 cites W2004554957 @default.
- W1122588891 cites W2013889224 @default.
- W1122588891 cites W2019850722 @default.
- W1122588891 cites W2021697429 @default.
- W1122588891 cites W2026309239 @default.
- W1122588891 cites W2042063390 @default.
- W1122588891 cites W2046339130 @default.
- W1122588891 cites W2046748497 @default.
- W1122588891 cites W2046938649 @default.
- W1122588891 cites W2049811310 @default.
- W1122588891 cites W2050745720 @default.
- W1122588891 cites W2052330831 @default.
- W1122588891 cites W2056400193 @default.
- W1122588891 cites W2058970523 @default.
- W1122588891 cites W2065335184 @default.
- W1122588891 cites W2071138716 @default.
- W1122588891 cites W2072820697 @default.
- W1122588891 cites W2077095962 @default.
- W1122588891 cites W2078153134 @default.
- W1122588891 cites W2080927210 @default.
- W1122588891 cites W2083939712 @default.
- W1122588891 cites W2089877883 @default.
- W1122588891 cites W2090439686 @default.
- W1122588891 cites W2101970047 @default.
- W1122588891 cites W2102070786 @default.
- W1122588891 cites W2112873358 @default.
- W1122588891 cites W2113495792 @default.
- W1122588891 cites W2116682907 @default.
- W1122588891 cites W2132264356 @default.
- W1122588891 cites W2136739656 @default.
- W1122588891 cites W2142671293 @default.
- W1122588891 cites W2150047295 @default.
- W1122588891 cites W2153120954 @default.
- W1122588891 cites W2159850238 @default.
- W1122588891 cites W2164014373 @default.
- W1122588891 cites W2170678600 @default.
- W1122588891 cites W2336770414 @default.
- W1122588891 cites W2395285345 @default.
- W1122588891 cites W71572777 @default.
- W1122588891 doi "https://doi.org/10.1016/b978-012194851-1/50029-9" @default.
- W1122588891 hasPublicationYear "2003" @default.
- W1122588891 type Work @default.
- W1122588891 sameAs 1122588891 @default.
- W1122588891 citedByCount "6" @default.
- W1122588891 countsByYear W11225888912021 @default.
- W1122588891 crossrefType "book-chapter" @default.
- W1122588891 hasAuthorship W1122588891A5005207519 @default.
- W1122588891 hasAuthorship W1122588891A5016309968 @default.
- W1122588891 hasAuthorship W1122588891A5060275560 @default.
- W1122588891 hasAuthorship W1122588891A5060459635 @default.
- W1122588891 hasConcept C142724271 @default.
- W1122588891 hasConcept C147483822 @default.
- W1122588891 hasConcept C159047783 @default.
- W1122588891 hasConcept C159654299 @default.
- W1122588891 hasConcept C182072434 @default.
- W1122588891 hasConcept C203014093 @default.
- W1122588891 hasConcept C2522874641 @default.
- W1122588891 hasConcept C2777546802 @default.
- W1122588891 hasConcept C2778692840 @default.
- W1122588891 hasConcept C2779134260 @default.
- W1122588891 hasConcept C3008058167 @default.
- W1122588891 hasConcept C32611913 @default.
- W1122588891 hasConcept C34343649 @default.
- W1122588891 hasConcept C45189115 @default.
- W1122588891 hasConcept C519248777 @default.
- W1122588891 hasConcept C524204448 @default.
- W1122588891 hasConcept C71924100 @default.
- W1122588891 hasConcept C7842527 @default.
- W1122588891 hasConcept C82988372 @default.
- W1122588891 hasConcept C86282344 @default.
- W1122588891 hasConcept C86803240 @default.
- W1122588891 hasConcept C89423630 @default.