FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1124615936> ?p ?o ?g. }

• W1124615936 endingPage "365" @default.
• W1124615936 startingPage "351" @default.
• W1124615936 abstract "The attachment of bacteria to mucosal surfaces is the initial event in the pathogenesis of several bacterial infections in the gastrointestinal tract. Macrophages also express substance P (SP) mRNA, which can be upregulated, leading to the release of SP when exposed to bacterial lipopolysaccharide (LPS) in vitro or during intestinal inflammation in vivo. Neuroimmune interactions and the enteric nervous system also play a major role in the pathogenesis of intestinal secretion due to Salmonella infection. Clostridium difficile toxin-mediated diarrhea and enterocolitis represent one of the best disease models, demonstrating how neuroimmune interactions modulate intestinal enterotoxin responses. Interestingly, mast cell-deficient mice have reduced toxin-A-associated ileal secretion and mucosal neutrophil infiltration, providing direct evidence of the importance of these multifunctional cells in the pathogenesis of enterotoxin-induced inflammatory diarrhea. Based on these considerations, macrophage-dependent mechanisms participate in the pathogenesis of toxin A-mediated enterocolitis. Studies using the Trichinella spiralis and Nippostrongylus brasiliensis animal models of parasitic infections provided important information not only on the pathophysiology of these diseases, but also on the outcome of immune cell-nerve interactions in the pathogenesis of diarrhea and intestinal inflammation. Valuable information from use of these models has had wide application in studies involving neuroimmune interactions in other forms of infectious diarrhea and inflammation. The successful inhibition of several types of infectious diarrhea and inflammation by neuropeptide and neuropeptide receptor antagonists in animal models opens the possibility that these or similar antagonists may be beneficial in the amelioration of the intestinal inflammation in human infection." @default.
• W1124615936 created "2016-06-24" @default.
• W1124615936 creator A5014760553 @default.
• W1124615936 date "2014-04-09" @default.
• W1124615936 modified "2023-09-23" @default.
• W1124615936 title "Neuroimmune Interactions and Pathogenesis of Intestinal Inflammation in Infectious Diseases" @default.
• W1124615936 cites W1499029747 @default.
• W1124615936 cites W1533899067 @default.
• W1124615936 cites W1547855439 @default.
• W1124615936 cites W1555576379 @default.
• W1124615936 cites W1568101899 @default.
• W1124615936 cites W1573332955 @default.
• W1124615936 cites W1590629056 @default.
• W1124615936 cites W1596664653 @default.
• W1124615936 cites W1603024961 @default.
• W1124615936 cites W1642315092 @default.
• W1124615936 cites W1748186123 @default.
• W1124615936 cites W1770775371 @default.
• W1124615936 cites W1808476113 @default.
• W1124615936 cites W1836576870 @default.
• W1124615936 cites W1839074689 @default.
• W1124615936 cites W1877520583 @default.
• W1124615936 cites W1899254857 @default.
• W1124615936 cites W1935443798 @default.
• W1124615936 cites W1965707610 @default.
• W1124615936 cites W1970017365 @default.
• W1124615936 cites W1979840603 @default.
• W1124615936 cites W1984269542 @default.
• W1124615936 cites W1989933960 @default.
• W1124615936 cites W1998889473 @default.
• W1124615936 cites W2001768751 @default.
• W1124615936 cites W2002370836 @default.
• W1124615936 cites W2003542646 @default.
• W1124615936 cites W2011843272 @default.
• W1124615936 cites W2012415800 @default.
• W1124615936 cites W2015252693 @default.
• W1124615936 cites W2020636522 @default.
• W1124615936 cites W2027237838 @default.
• W1124615936 cites W2027441347 @default.
• W1124615936 cites W2027977018 @default.
• W1124615936 cites W2031004883 @default.
• W1124615936 cites W2033961915 @default.
• W1124615936 cites W2037046147 @default.
• W1124615936 cites W2037963721 @default.
• W1124615936 cites W2040961976 @default.
• W1124615936 cites W2041105692 @default.
• W1124615936 cites W2047667187 @default.
• W1124615936 cites W2048240573 @default.
• W1124615936 cites W2050186268 @default.
• W1124615936 cites W2052384425 @default.
• W1124615936 cites W2055944577 @default.
• W1124615936 cites W2056247510 @default.
• W1124615936 cites W2060999100 @default.
• W1124615936 cites W2061137185 @default.
• W1124615936 cites W2061594143 @default.
• W1124615936 cites W2065597738 @default.
• W1124615936 cites W2068139901 @default.
• W1124615936 cites W2069482408 @default.
• W1124615936 cites W2069800046 @default.
• W1124615936 cites W2072343797 @default.
• W1124615936 cites W2072896519 @default.
• W1124615936 cites W2073748343 @default.
• W1124615936 cites W2074896196 @default.
• W1124615936 cites W2076641599 @default.
• W1124615936 cites W2076962060 @default.
• W1124615936 cites W2080557077 @default.
• W1124615936 cites W2092250377 @default.
• W1124615936 cites W2093531619 @default.
• W1124615936 cites W2095488499 @default.
• W1124615936 cites W2097928971 @default.
• W1124615936 cites W2101088818 @default.
• W1124615936 cites W2108340840 @default.
• W1124615936 cites W2109676094 @default.
• W1124615936 cites W2115065580 @default.
• W1124615936 cites W2121614197 @default.
• W1124615936 cites W2129815268 @default.
• W1124615936 cites W2136993229 @default.
• W1124615936 cites W2142519377 @default.
• W1124615936 cites W2149842264 @default.
• W1124615936 cites W2151116384 @default.
• W1124615936 cites W2151125746 @default.
• W1124615936 cites W2153532523 @default.
• W1124615936 cites W2154252519 @default.
• W1124615936 cites W2154976865 @default.
• W1124615936 cites W2157919311 @default.
• W1124615936 cites W2158947246 @default.
• W1124615936 cites W2159643132 @default.
• W1124615936 cites W2169372294 @default.
• W1124615936 cites W2169731572 @default.
• W1124615936 cites W2185555626 @default.
• W1124615936 cites W2186373601 @default.
• W1124615936 cites W2315155052 @default.
• W1124615936 cites W2321858688 @default.
• W1124615936 cites W2337972425 @default.
• W1124615936 cites W4210983716 @default.
• W1124615936 cites W4246026327 @default.
• W1124615936 doi "https://doi.org/10.1128/9781555817848.ch19" @default.
• W1124615936 hasPublicationYear "2014" @default.

• next