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- W11256099 abstract "This chapter provides an overview of conditioned hypoglycemia and conditioned insulin secretion. Conditioned hypoglycemia is a relatively rapid decrease of blood glucose that occurs over a short period of time. For this to be accomplished, there are a few possibilities. There must be a net increase of glucose utilization/uptake by tissues and/or a net decrease of glucose entry into the blood from the liver and gut. These in turn could be accomplished either by a decreased activity of hyperglycemic reflexes hormones or else an increased activity of hypoglycemic ones. When insulin is administered to animals during conditioning, some of it gets into the cerebrospinal fluid (CSF) and triggers the secretion of endogenous insulin. Conditioned hypoglycemia would develop if there is an increase of CSF insulin associated with a neutral stimulus, without the necessity of a change of peripheral insulin or peripheral glucose level. Even though plasma insulin normally fluctuates rapidly, CSF insulin changes very slowly. Thus, the brain may not normally experience rapid increases of insulin as occurring on conditioning trials." @default.
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- W11256099 date "1983-01-01" @default.
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- W11256099 title "Conditioned Hypoglycemia and Conditioned Insulin Secretion" @default.
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- W11256099 doi "https://doi.org/10.1016/b978-0-12-027310-2.50026-8" @default.
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