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- W112683668 abstract "Transfection studies in human osteosarcoma cells have demonstrated that the enzyme 5-lipoxygenase (5-LO) and the integral membrane protein 5-lipoxygenase activating protein (FLAP) are both required for the cellular synthesis of leukotrienes (LTs) (1). Consequently compounds which directly inhibit 5-LO (2) or specifically interact with FLAP (3,4) arc potent inhibitors of LT synthesis and are currently being asseed for the treatment of diseases in which LTs are implicated." @default.
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- W112683668 date "1997-01-01" @default.
- W112683668 modified "2023-10-15" @default.
- W112683668 title "The Effect of 5-Lipoxygenase-Activating Protein (Flap) on Substrate Utilization by 5-Lipoxygenase" @default.
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- W112683668 doi "https://doi.org/10.1007/978-1-4615-5325-0_21" @default.
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