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• W1126872217 abstract "Red yeast rice has become one of the leading cholesterol-lowering ingredients used in food supplements throughout the world. However, one active compound of red yeast rice, monacolin K (also known as lovastatin), was the first statin commercialised by pharmaceutical companies. Therefore, monacolin K may be considered a drug in several European countries, leading to uncertainties regarding the legal status of red yeast rice-containing food supplements. Despite the fact that red yeast rice is a borderline ingredient between food supplements and drugs, the European Food Safety Authority has recognised the cholesterol-lowering properties of monacolin K in the evaluation of two health claims, and the European Commission has validated a health claim related to monacolin K and the maintenance of normal blood LDL-cholesterol concentration in Regulation (EC) No. 432/2012. The condition of use of this claim, notably that the daily intake of monacolin K imposed by this regulation can be considered a medicinal dosage, is open to criticism. However, the validation of a health claim related to monacolin K by the European Commission has led to a unique situation in which an authorised health claim cannot be used in most European countries, due to a dosage of monacolin K that may lead to the requalification of red yeast rice-containing food supplements as a drug by function." @default.
• W1126872217 created "2016-06-24" @default.
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• W1126872217 date "2015-01-01" @default.
• W1126872217 modified "2023-09-27" @default.
• W1126872217 title "Authorised EU health claim for red yeast rice" @default.
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• W1126872217 doi "https://doi.org/10.1016/b978-1-78242-382-9.00008-6" @default.
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