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• W1127803968 abstract "Lipopolysaccharide (LPS) is the major component of the outer membrane of gram-negative bacteria and consists of three distinct structural domains: lipid A, a nonrepeating “core” oligosaccharide, and a distal repeated O-antigen polysaccharide. This chapter discusses the structure of the three regions, in order, as they extend out from the outer membrane, focusing on regulated alterations, modifications, and/or substitutions. The biosynthetic enzymes are either constitutively active or regulated by a variety of two-component regulatory systems, including PhoR/PhoB, PmrA/PmrB and/or PhoP/PhoQ. Deletion of IpxT in Escherichia coli resulted in an increase in sensitivity to the cationic antimicrobial peptides (AMPs) polymyxin B, although experiments elucidating roles for lpxT in overall pathogenesis have yet to be undertaken. The chapter explores the regulation of one particular modification, that of phosphorylcholine (ChoP), on Haemophilus and Neisseria lipooligosaccharide (LOS). Regulation of LPS core biosynthesis is not well understood, although some of the regulatory mechanisms for biosynthesis of Kdo and inner and outer core are emerging. The current evidence based on genetic and biophysical interaction studies of the Lpt proteins supports the transenvelope model. Further studies into the regulation of LPS should help provide a link between signals in the environment and the resulting outer membrane composition that are likely to have the most impact on host-pathogen interactions." @default.
• W1127803968 created "2016-06-24" @default.
• W1127803968 creator A5009807217 @default.
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• W1127803968 date "2016-09-19" @default.
• W1127803968 modified "2023-09-26" @default.
• W1127803968 title "Regulation of Lipopolysaccharide Modifications and Antimicrobial Peptide Resistance" @default.
• W1127803968 cites W1482725507 @default.
• W1127803968 cites W1483384893 @default.
• W1127803968 cites W1498078214 @default.
• W1127803968 cites W1498734911 @default.
• W1127803968 cites W1501009591 @default.
• W1127803968 cites W1510619113 @default.
• W1127803968 cites W1533284075 @default.
• W1127803968 cites W1568638001 @default.
• W1127803968 cites W1573220291 @default.
• W1127803968 cites W1583732036 @default.
• W1127803968 cites W1595275633 @default.
• W1127803968 cites W1601760404 @default.
• W1127803968 cites W1607386402 @default.
• W1127803968 cites W1697620700 @default.
• W1127803968 cites W1698100182 @default.
• W1127803968 cites W1743939834 @default.
• W1127803968 cites W1751383774 @default.
• W1127803968 cites W1785999156 @default.
• W1127803968 cites W1786268878 @default.
• W1127803968 cites W1824848105 @default.
• W1127803968 cites W1875336248 @default.
• W1127803968 cites W1881141831 @default.
• W1127803968 cites W1886645137 @default.
• W1127803968 cites W1891980138 @default.
• W1127803968 cites W1892445636 @default.
• W1127803968 cites W1893663036 @default.
• W1127803968 cites W1920922495 @default.
• W1127803968 cites W1924337667 @default.
• W1127803968 cites W1946545751 @default.
• W1127803968 cites W1947508812 @default.
• W1127803968 cites W1963867445 @default.
• W1127803968 cites W1964343287 @default.
• W1127803968 cites W1965237471 @default.
• W1127803968 cites W1966317849 @default.
• W1127803968 cites W1966350980 @default.
• W1127803968 cites W1972760283 @default.
• W1127803968 cites W1972993814 @default.
• W1127803968 cites W1975141356 @default.
• W1127803968 cites W1975380012 @default.
• W1127803968 cites W1977338358 @default.
• W1127803968 cites W1978030581 @default.
• W1127803968 cites W1978955250 @default.
• W1127803968 cites W1979687902 @default.
• W1127803968 cites W1980917471 @default.
• W1127803968 cites W1980967869 @default.
• W1127803968 cites W1981319306 @default.
• W1127803968 cites W1982498329 @default.
• W1127803968 cites W1985027846 @default.
• W1127803968 cites W1985073212 @default.
• W1127803968 cites W1988121517 @default.
• W1127803968 cites W1989005656 @default.
• W1127803968 cites W1991564172 @default.
• W1127803968 cites W1991892385 @default.
• W1127803968 cites W1992738816 @default.
• W1127803968 cites W1993513102 @default.
• W1127803968 cites W1993878548 @default.
• W1127803968 cites W1994980332 @default.
• W1127803968 cites W1995781377 @default.
• W1127803968 cites W1996901586 @default.
• W1127803968 cites W1997494954 @default.
• W1127803968 cites W2002252371 @default.
• W1127803968 cites W2003112779 @default.
• W1127803968 cites W2003684564 @default.
• W1127803968 cites W2004682883 @default.
• W1127803968 cites W2004927612 @default.
• W1127803968 cites W2005835947 @default.
• W1127803968 cites W2006463424 @default.
• W1127803968 cites W2006697711 @default.
• W1127803968 cites W2009335524 @default.
• W1127803968 cites W2010272783 @default.
• W1127803968 cites W2010519412 @default.
• W1127803968 cites W2012487674 @default.
• W1127803968 cites W2014961798 @default.
• W1127803968 cites W2014973946 @default.
• W1127803968 cites W2015205329 @default.
• W1127803968 cites W2016411536 @default.
• W1127803968 cites W2017370646 @default.
• W1127803968 cites W2021345678 @default.
• W1127803968 cites W2023788713 @default.
• W1127803968 cites W2027129974 @default.
• W1127803968 cites W2028372896 @default.
• W1127803968 cites W2028556579 @default.
• W1127803968 cites W2030542329 @default.
• W1127803968 cites W2030693257 @default.
• W1127803968 cites W2030794862 @default.
• W1127803968 cites W2032628165 @default.
• W1127803968 cites W2033509170 @default.
• W1127803968 cites W2034541624 @default.

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