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- W11299776 abstract "Multiple sclerosis is the most frequent chronic inflammatory, demyelinating and neurodegenerative disease in young adults, but has no definitive pharmacological treatment. It is a heterogeneous disease from the immunological, neuropathological and clinical point of view, as well as in terms of its response to different therapies. Over the last two decades, pharmacology has focused on developing drugs that are capable of modifying the course of this disease, with the aim of reducing the frequency of the outbreaks and the speed at which the disability produced by the disease progresses. Nevertheless, today, there are no drugs that are capable of offering a curative effect that can fully stabilise the disease, and neuroprotective and neuroreparative strategies are still in their early stages. In this work we carry out a critical review of the different pathogenic paths involved in multiple sclerosis and we discuss the different pharmacological approaches that have been followed, based on the clinical trials that are currently being conducted. In the near future it is to be expected that, first, we will manage to stabilise the disease completely and, later, recover some of the functions altered by this disease. Research is being conducted at such a rate that we have to be optimistic and think that soon we will be able to improve the situation of those who suffer from the disease." @default.
- W11299776 created "2016-06-24" @default.
- W11299776 creator A5033263748 @default.
- W11299776 creator A5034641904 @default.
- W11299776 creator A5064987103 @default.
- W11299776 creator A5082302756 @default.
- W11299776 date "2011-01-01" @default.
- W11299776 modified "2023-09-26" @default.
- W11299776 title "Dianas farmacológicas en la esclerosis múltiple" @default.
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- W11299776 doi "https://doi.org/10.33588/rn.5301.2011061" @default.
- W11299776 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21678322" @default.
- W11299776 hasPublicationYear "2011" @default.
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