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- W11302680 abstract "Background: Obstructive sleep apnea (OSA) has been associated with atrial enlargement in response to high arterial and pulmonary pressures and increased sympathetic tone. Continuous positive airway pressure (CPAP) is the gold standard treatment for OSA although its impact on atrial electrical remodeling has not been investigated. Signal average P-wave (SAPW) is a non-invasive quantitative method to determine P-wave duration, an accepted marker for atrial electrical remodeling. Our objective was to determine whether CPAP induces reverse atrial electrical remodeling in patients with severe OSA. Methods: Prospective study in consecutive patients attending the Sleep Clinic at our institution. All patients underwent full polysomnography. OSA-negative and severe OSA were defined as apnea-hypopnea index (AHI) < 5 events/hour and AHI ≥ 30 events/hour, respectively. In severe OSA patients, SAPW was determined pre- and post-intervention with CPAP. In OSA-negative controls, SAPW was recorded at baseline and 4-6 week..." @default.
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- W11302680 date "2011-11-22" @default.
- W11302680 modified "2023-09-26" @default.
- W11302680 title "Abstract 13232: Reverse Atrial Electrical Remodeling Induced by Continuous Positive Airway Pressure in Patients with Severe Obstructive Sleep Apnea" @default.
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