FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W113284759> ?p ?o ?g. }

• W113284759 endingPage "F1053" @default.
• W113284759 startingPage "F1037" @default.
• W113284759 abstract "Using an in vivo rat model of unilateral renal ischemia, we previously showed that the expression and distribution of fibronectin (FN), a major glycoprotein of plasma and the extracellular matrix, dramatically changes in response to ischemia-reperfusion. In the distal nephron in particular, FN accumulates in tubular lumens, where it may contribute to obstruction. In the present study, we examine whether the tubular FN is the plasma or cellular form, each of which is produced by alternative splicing of a single gene transcript. We demonstrate that FN in tubular lumens does not contain the extra type III A (EIIIA) and/or the extra type III B (EIIIB) region, both of which are unique to cellular FN. It does, however, contain the V95 region, which in the rat is a component of FNs in both plasma and the extracellular matrix. Expression of FN containing EIIIA increases dramatically in the renal interstitium after ischemic injury and continues to be produced at high levels 6 wk later. V95-containing FN also increases in the interstitial space, albeit more slowly and at lower levels than FN containing EIIIA; it also persists 6 wk later. FN containing the EIIIB region is not expressed in the injured kidney. The presence of V95 but not the EIIIA or EIIIB regions of FN in tubular lumens identifies the origin of FN in this location as the plasma; tubular FN is ultimately voided in the urine. The data indicate that both plasma and cellular FNs containing the V95 and/or EIIIA regions may contribute to the pathogenesis of acute renal failure and to the repair of the injured kidney." @default.
• W113284759 created "2016-06-24" @default.
• W113284759 creator A5053647122 @default.
• W113284759 creator A5077385289 @default.
• W113284759 creator A5089781525 @default.
• W113284759 date "2001-06-01" @default.
• W113284759 modified "2023-10-15" @default.
• W113284759 title "Expression of fibronectin splice variants in the postischemic rat kidney" @default.
• W113284759 cites W107731324 @default.
• W113284759 cites W1505978562 @default.
• W113284759 cites W1524114372 @default.
• W113284759 cites W1537286163 @default.
• W113284759 cites W1558930301 @default.
• W113284759 cites W1604903306 @default.
• W113284759 cites W1605153099 @default.
• W113284759 cites W1891794422 @default.
• W113284759 cites W1962262283 @default.
• W113284759 cites W1970516412 @default.
• W113284759 cites W1989836067 @default.
• W113284759 cites W1993925269 @default.
• W113284759 cites W1994408107 @default.
• W113284759 cites W1999916897 @default.
• W113284759 cites W2000698961 @default.
• W113284759 cites W2000826743 @default.
• W113284759 cites W2012008369 @default.
• W113284759 cites W2018128871 @default.
• W113284759 cites W2023648877 @default.
• W113284759 cites W2027693573 @default.
• W113284759 cites W2034055101 @default.
• W113284759 cites W2044008951 @default.
• W113284759 cites W2044144438 @default.
• W113284759 cites W2048055673 @default.
• W113284759 cites W2050806791 @default.
• W113284759 cites W2053984681 @default.
• W113284759 cites W2055560656 @default.
• W113284759 cites W2056813629 @default.
• W113284759 cites W2063338234 @default.
• W113284759 cites W2066188919 @default.
• W113284759 cites W2066665315 @default.
• W113284759 cites W2067729477 @default.
• W113284759 cites W2072558376 @default.
• W113284759 cites W2080568372 @default.
• W113284759 cites W2090262709 @default.
• W113284759 cites W2092195476 @default.
• W113284759 cites W2096081784 @default.
• W113284759 cites W2096280264 @default.
• W113284759 cites W2100837269 @default.
• W113284759 cites W2102915331 @default.
• W113284759 cites W2103572856 @default.
• W113284759 cites W2107839231 @default.
• W113284759 cites W2109088595 @default.
• W113284759 cites W2113456660 @default.
• W113284759 cites W2123832217 @default.
• W113284759 cites W2126163284 @default.
• W113284759 cites W2147368533 @default.
• W113284759 cites W2164620775 @default.
• W113284759 cites W2165830726 @default.
• W113284759 cites W2172208039 @default.
• W113284759 cites W2183278437 @default.
• W113284759 cites W2315077022 @default.
• W113284759 cites W2336109487 @default.
• W113284759 cites W2339016725 @default.
• W113284759 cites W2398689627 @default.
• W113284759 cites W3180990364 @default.
• W113284759 cites W4236514815 @default.
• W113284759 cites W71897710 @default.
• W113284759 doi "https://doi.org/10.1152/ajprenal.2001.280.6.f1037" @default.
• W113284759 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11352844" @default.
• W113284759 hasPublicationYear "2001" @default.
• W113284759 type Work @default.
• W113284759 sameAs 113284759 @default.
• W113284759 citedByCount "44" @default.
• W113284759 countsByYear W1132847592012 @default.
• W113284759 countsByYear W1132847592013 @default.
• W113284759 countsByYear W1132847592014 @default.
• W113284759 countsByYear W1132847592015 @default.
• W113284759 countsByYear W1132847592016 @default.
• W113284759 countsByYear W1132847592019 @default.
• W113284759 countsByYear W1132847592021 @default.
• W113284759 countsByYear W1132847592022 @default.
• W113284759 countsByYear W1132847592023 @default.
• W113284759 crossrefType "journal-article" @default.
• W113284759 hasAuthorship W113284759A5053647122 @default.
• W113284759 hasAuthorship W113284759A5077385289 @default.
• W113284759 hasAuthorship W113284759A5089781525 @default.
• W113284759 hasConcept C104317684 @default.
• W113284759 hasConcept C105580179 @default.
• W113284759 hasConcept C126322002 @default.
• W113284759 hasConcept C134018914 @default.
• W113284759 hasConcept C142724271 @default.
• W113284759 hasConcept C185592680 @default.
• W113284759 hasConcept C189165786 @default.
• W113284759 hasConcept C194583182 @default.
• W113284759 hasConcept C2780091579 @default.
• W113284759 hasConcept C28406088 @default.
• W113284759 hasConcept C541997718 @default.
• W113284759 hasConcept C55493867 @default.
• W113284759 hasConcept C71924100 @default.

• next