FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1133982743> ?p ?o ?g. }

• W1133982743 endingPage "159" @default.
• W1133982743 startingPage "148" @default.
• W1133982743 abstract "Brain sex differences are found in nearly every region of the brain and fundamental to sexually dimorphic behaviors as well as disorders of the brain and behavior. These differences are organized during gestation and early adolescence and detectable prior to puberty. Endocrine disrupting compounds (EDCs) interfere with hormone action and are thus prenatal exposure is hypothesized to disrupt the formation of sex differences, and contribute to the increased prevalence of pediatric neuropsychiatric disorders that present with a sex bias.Available evidence for the ability of EDCs to impact the emergence of brain sex differences in the rodent brain was reviewed here, with a focus on effects detected at or before puberty.The peer-reviewed literature was searched using PubMed, and all relevant papers published by January 31, 2015 were incorporated. Endpoints of interest included molecular cellular and neuroanatomical effects. Studies on behavioral endpoints were not included because numerous reviews of that literature are available.The hypothalamus was found to be particularly affected by estrogenic EDCs in a sex, time, and exposure dependent manner. The hippocampus also appears vulnerable to endocrine disruption by BPA and PCBs although there is little evidence from the pre-pubertal literature to make any conclusions about sex-specific effects. Gestational EDC exposure can alter fetal neurogenesis and gene expression throughout the brain including the cortex and cerebellum. The available literature primarily focuses on a few, well characterized EDCs, but little data is available for emerging contaminants.The developmental EDC exposure literature demonstrates evidence of altered neurodevelopment as early as fetal life, with sex specific effects observed throughout the brain even before puberty." @default.
• W1133982743 created "2016-06-24" @default.
• W1133982743 creator A5056745479 @default.
• W1133982743 creator A5062731941 @default.
• W1133982743 date "2016-06-01" @default.
• W1133982743 modified "2023-10-14" @default.
• W1133982743 title "Assessment of sex specific endocrine disrupting effects in the prenatal and pre-pubertal rodent brain" @default.
• W1133982743 cites W115538672 @default.
• W1133982743 cites W1539176226 @default.
• W1133982743 cites W1543786573 @default.
• W1133982743 cites W1583176296 @default.
• W1133982743 cites W1848381484 @default.
• W1133982743 cites W1849312848 @default.
• W1133982743 cites W1941975926 @default.
• W1133982743 cites W1964822650 @default.
• W1133982743 cites W1969487024 @default.
• W1133982743 cites W1972155984 @default.
• W1133982743 cites W1976629102 @default.
• W1133982743 cites W1977171829 @default.
• W1133982743 cites W1977689564 @default.
• W1133982743 cites W1981454226 @default.
• W1133982743 cites W1983378305 @default.
• W1133982743 cites W1994836833 @default.
• W1133982743 cites W1996002076 @default.
• W1133982743 cites W1996996841 @default.
• W1133982743 cites W1997303320 @default.
• W1133982743 cites W1998771264 @default.
• W1133982743 cites W1999658072 @default.
• W1133982743 cites W2001183909 @default.
• W1133982743 cites W2002138184 @default.
• W1133982743 cites W2003293875 @default.
• W1133982743 cites W2003316529 @default.
• W1133982743 cites W2004610071 @default.
• W1133982743 cites W2005959147 @default.
• W1133982743 cites W2009748009 @default.
• W1133982743 cites W2016639841 @default.
• W1133982743 cites W2019356489 @default.
• W1133982743 cites W2020691637 @default.
• W1133982743 cites W2023855504 @default.
• W1133982743 cites W2025956906 @default.
• W1133982743 cites W2027407596 @default.
• W1133982743 cites W2027431314 @default.
• W1133982743 cites W2032450342 @default.
• W1133982743 cites W2037056332 @default.
• W1133982743 cites W2038609674 @default.
• W1133982743 cites W2039617877 @default.
• W1133982743 cites W2040073285 @default.
• W1133982743 cites W2040575203 @default.
• W1133982743 cites W2041440840 @default.
• W1133982743 cites W2044203150 @default.
• W1133982743 cites W2044219552 @default.
• W1133982743 cites W2044819518 @default.
• W1133982743 cites W2045499624 @default.
• W1133982743 cites W2045594266 @default.
• W1133982743 cites W2046232375 @default.
• W1133982743 cites W2048085345 @default.
• W1133982743 cites W2048655519 @default.
• W1133982743 cites W2050783031 @default.
• W1133982743 cites W2050976238 @default.
• W1133982743 cites W2052517186 @default.
• W1133982743 cites W2054121574 @default.
• W1133982743 cites W2056736352 @default.
• W1133982743 cites W2059421349 @default.
• W1133982743 cites W2060712561 @default.
• W1133982743 cites W2061043446 @default.
• W1133982743 cites W2062318487 @default.
• W1133982743 cites W2062975341 @default.
• W1133982743 cites W2066839073 @default.
• W1133982743 cites W2068757410 @default.
• W1133982743 cites W2071759715 @default.
• W1133982743 cites W2073029345 @default.
• W1133982743 cites W2075811276 @default.
• W1133982743 cites W2078148104 @default.
• W1133982743 cites W2079119026 @default.
• W1133982743 cites W2079724894 @default.
• W1133982743 cites W2082213808 @default.
• W1133982743 cites W2083314087 @default.
• W1133982743 cites W2086971054 @default.
• W1133982743 cites W2088635969 @default.
• W1133982743 cites W2089588218 @default.
• W1133982743 cites W2089807318 @default.
• W1133982743 cites W2091563202 @default.
• W1133982743 cites W2093253653 @default.
• W1133982743 cites W2094262803 @default.
• W1133982743 cites W2094405673 @default.
• W1133982743 cites W2095396181 @default.
• W1133982743 cites W2097292457 @default.
• W1133982743 cites W2101300382 @default.
• W1133982743 cites W2103075537 @default.
• W1133982743 cites W2105938068 @default.
• W1133982743 cites W2106883177 @default.
• W1133982743 cites W2109818577 @default.
• W1133982743 cites W2112484512 @default.
• W1133982743 cites W2112827416 @default.
• W1133982743 cites W2112997651 @default.
• W1133982743 cites W2118947118 @default.
• W1133982743 cites W2124958203 @default.
• W1133982743 cites W2124972415 @default.

• next