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• W1134511704 abstract "Publisher Summary Viral hepatitis A, B, C, D, and E are important public health problems in China. However, hepatitis B virus (HBV) and hepatitis C virus (HCV) overshadow the other viruses because of their severe and frequent squeal as chronic hepatitis, cirrhosis, and primary hepatocellular carcinoma (HCC), which can seriously imperil the health and life of infected individuals. HCV is the major etiology of parenteral non-A hepatitis and non-B hepatitis. Since diagnostic reagents became available to detect HCV antibody (anti-HCV) and HCV RNA, the epidemiology of HCV infection has been investigated around the world and the basic clinical studies on HCV have progressed rapidly. Epidemiological patterns for HBV and HCV infections in China are different from those in other advanced countries in several ways, such as high prevalence of infection, high ratio of chronic to acute infection, high risk of maternal–infant transmission, high rate of mutation of viral genes, and poor response to interferon (IFN) treatment. It may be preferable to use monotherapy approaches, such as lamivudine. Interferon is usually ineffective in Chinese patients because genotype lb predominates in this population. The need to continue prevention programs and childhood vaccination for HBV and HCV is essential." @default.
• W1134511704 created "2016-06-24" @default.
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• W1134511704 date "2003-01-01" @default.
• W1134511704 modified "2023-09-25" @default.
• W1134511704 title "Molecular and serum epidemiology of HBV and HCV infection and the impact of antiviral agents in China" @default.
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• W1134511704 doi "https://doi.org/10.1016/b978-044450986-4/50053-9" @default.
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