FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W113485285> ?p ?o ?g. }

• W113485285 endingPage "352" @default.
• W113485285 startingPage "341" @default.
• W113485285 abstract "The use of tubes as an alternative to primary nerve suture in fresh nerve transections has been introduced as a biologic approach to nerve injuries, creating optimal conditions for axonal regeneration over a short empty space intentionally created between the proximal and distal nerve ends. The idea may seem controversial and has been criticized using the arguments that silicone in itself may create problems like inflammation and the tube may compress the nerve ends. With the use of appropriately sized tubes for bridging a maximum 5-mm gap in human median and ulnar nerves, the authors have found the technique to be useful and persistent at follow-up examinations for up to 4 to 5 years. In addition, from the intellectual point of view, the principle illustrates the concept by which emphasis is placed on the intrinsic healing capacities of the nerve rather than on the technical skill of the surgeon. The thin mesothelial lining found around the silicone tube lacks primary inflammatory signs at follow-up after 1 year, and no signs of compression are seen. It may be an advantage because it allows sliding of the repair site against the surrounding tissues. Tubes made of bioresorbable material may seem ideal, but they may introduce new problems associated with the resorption process in terms of a substantial unrestricted macrophage invasion, fibrosis, and disorganized axonal growth. For an extended nerve defect, the use of autologous nerve grafts is still the gold standard, because no tubular conduit or other conduit has so far proved equal to autologous nerve grafts, at least not for reconstruction of human median and ulnar nerve trunks. Alternatives other than tubes are currently being developed and investigated. For the future, the use of tubes for repair and reconstruction of nerves may have interesting potentials, because such a structure allows several types of tissue engineering. Various matrices containing, for instance, appropriate cells, factors, or other stimulating agents can be introduced in the tube lumen and can also be incorporated in a slow-release form in the walls of the tube and manipulated. Cultured Schwann cells or other cellular components, with or without manipulated production machinery, are probably the cells of choice for introduction in the tubes. Tubes may thus prove to be interesting alternatives to conventional repair techniques for primary repair of nerves and for reconstruction of segmental defects and for neuroma treatment in the future." @default.
• W113485285 created "2016-06-24" @default.
• W113485285 creator A5013464823 @default.
• W113485285 creator A5054874494 @default.
• W113485285 date "2001-04-01" @default.
• W113485285 modified "2023-10-18" @default.
• W113485285 title "Use of Tubes in Peripheral Nerve Repair" @default.
• W113485285 cites W111273388 @default.
• W113485285 cites W121816017 @default.
• W113485285 cites W143657778 @default.
• W113485285 cites W1485465421 @default.
• W113485285 cites W1761268335 @default.
• W113485285 cites W1898813276 @default.
• W113485285 cites W1964325390 @default.
• W113485285 cites W1964810819 @default.
• W113485285 cites W1965143348 @default.
• W113485285 cites W1965352187 @default.
• W113485285 cites W1972729557 @default.
• W113485285 cites W1977302956 @default.
• W113485285 cites W1978424558 @default.
• W113485285 cites W1979782989 @default.
• W113485285 cites W1983349138 @default.
• W113485285 cites W1983398893 @default.
• W113485285 cites W1983794951 @default.
• W113485285 cites W1984218330 @default.
• W113485285 cites W1986062352 @default.
• W113485285 cites W1988127448 @default.
• W113485285 cites W1991282138 @default.
• W113485285 cites W1991330264 @default.
• W113485285 cites W1991592406 @default.
• W113485285 cites W1991993915 @default.
• W113485285 cites W1996353258 @default.
• W113485285 cites W1996648228 @default.
• W113485285 cites W1997905786 @default.
• W113485285 cites W1998884668 @default.
• W113485285 cites W1999090141 @default.
• W113485285 cites W1999337953 @default.
• W113485285 cites W2001952916 @default.
• W113485285 cites W2003691260 @default.
• W113485285 cites W2004012808 @default.
• W113485285 cites W2004611738 @default.
• W113485285 cites W2005539418 @default.
• W113485285 cites W2006363780 @default.
• W113485285 cites W2009202456 @default.
• W113485285 cites W2010161113 @default.
• W113485285 cites W2011320838 @default.
• W113485285 cites W2015696209 @default.
• W113485285 cites W2017013047 @default.
• W113485285 cites W2017901957 @default.
• W113485285 cites W2018121061 @default.
• W113485285 cites W2019403020 @default.
• W113485285 cites W2021180752 @default.
• W113485285 cites W2026391444 @default.
• W113485285 cites W2026963955 @default.
• W113485285 cites W2027862144 @default.
• W113485285 cites W2029431784 @default.
• W113485285 cites W2034127040 @default.
• W113485285 cites W2038997019 @default.
• W113485285 cites W2041993072 @default.
• W113485285 cites W2044172849 @default.
• W113485285 cites W2046445375 @default.
• W113485285 cites W2048670135 @default.
• W113485285 cites W2063525911 @default.
• W113485285 cites W2064963239 @default.
• W113485285 cites W2068659604 @default.
• W113485285 cites W2069198916 @default.
• W113485285 cites W2072012268 @default.
• W113485285 cites W2073861900 @default.
• W113485285 cites W2076397220 @default.
• W113485285 cites W2080965889 @default.
• W113485285 cites W2081272290 @default.
• W113485285 cites W2082180854 @default.
• W113485285 cites W2082805021 @default.
• W113485285 cites W2083069889 @default.
• W113485285 cites W2085488239 @default.
• W113485285 cites W2086691389 @default.
• W113485285 cites W2088336696 @default.
• W113485285 cites W2089640591 @default.
• W113485285 cites W2092274103 @default.
• W113485285 cites W2093229003 @default.
• W113485285 cites W2093771846 @default.
• W113485285 cites W2105454620 @default.
• W113485285 cites W2108995746 @default.
• W113485285 cites W2110496174 @default.
• W113485285 cites W2114216374 @default.
• W113485285 cites W2116477332 @default.
• W113485285 cites W2119590852 @default.
• W113485285 cites W2121777527 @default.
• W113485285 cites W2124243591 @default.
• W113485285 cites W2124705422 @default.
• W113485285 cites W2126961438 @default.
• W113485285 cites W2130055311 @default.
• W113485285 cites W2136511265 @default.
• W113485285 cites W2138909102 @default.
• W113485285 cites W2141887970 @default.
• W113485285 cites W2145277005 @default.
• W113485285 cites W2154309821 @default.
• W113485285 cites W2156229286 @default.

• next