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- W1137408069 endingPage "63" @default.
- W1137408069 startingPage "57" @default.
- W1137408069 abstract "Reports from multiple laboratories have now been published analyzing the critical nature of the caspase cleavage site of amyloid-β protein precursor (AβPP) for cell death induction, synaptic loss, hippocampal atrophy, long-term potentiation, memory loss, neophobia, and other aspects of the Alzheimer's phenotype. Here we review the results and implications of these studies for the understanding of Alzheimer's disease pathophysiology and the potential development of therapeutics that target this site in AβPP." @default.
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- W1137408069 date "2010-09-28" @default.
- W1137408069 modified "2023-09-23" @default.
- W1137408069 title "Importance of the Caspase Cleavage Site in Amyloid-β Protein Precursor" @default.
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- W1137408069 doi "https://doi.org/10.3233/jad-2010-100537" @default.
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