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- W1140197029 abstract "Objective to examine the effects of daily supplements of vitamin D on specific cytokine levels that play a role in the host inflammatory response Methods: Double-blinded, placebo-controlled feasibility pilot study among120 healthy Mongolian children in Ulaanbaatar to assigned either to 800IU of vitamin D daily or identical-looking placebo. The follow-up was 6 months. We measured levels of 21 different cytokines (IL-1b, 2, 4, 5, 6, 7, 8, 10, 12p70, 13, 17a, 21, 23, GM-CSF, IFN-γ, TNF-α, ITAC, Fractalkine, MIP1a, MIP1b, MIP3a) in the subsamples of serum of participants at baseline and the follow-up visit. Results: The baseline 25(OH)D level was 7±4 ng/mL. The cytokine levels were not different between placebo group and vitamin D group at baseline. After 6 month of follow up the cytokine levels were not statistically significant except the levels of Granulocyte-macrophage colony-stimulating factor (GM-CSF) between vitamin D and Placebo group post-treatment (p=0.03). Conclusions Our preliminary data show that vitamin D repletion does not change background T cell parameters in Mongolian school age children although this conclusion is limited by its small sample size and perhaps kit sensitivity issue in measuring cytokine levels in children." @default.
- W1140197029 created "2016-06-24" @default.
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- W1140197029 date "2015-04-01" @default.
- W1140197029 modified "2023-09-23" @default.
- W1140197029 title "Serum cytokine levels in healthy Mongolian school‐age children randomized to either vitamin D or placebo." @default.
- W1140197029 doi "https://doi.org/10.1096/fasebj.29.1_supplement.729.8" @default.
- W1140197029 hasPublicationYear "2015" @default.
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