FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1141258917> ?p ?o ?g. }

• W1141258917 endingPage "22" @default.
• W1141258917 startingPage "20" @default.
• W1141258917 abstract "Recent evidence would indicate that high serum uric acid (SUA) levels can be a significant and independent risk factor for hypertension and cardiovascular diseases, such as ischemic heart disease and heart failure. In the last few years an independent risk relationship between hyperuricemia, cardiovascular disease and mortality has also been reported. Hyperuricemia has been shown as an independent risk factor for acute myocardial infarction and an independent and conjoint association of either gout and SUA with total and cardiovascular mortality has been reported, with mortality impact in gout patients increasing with rising SUA concentrations, even for SUA levels in the normal to high range. These findings prompted a growing research interest on the possible benefits of uric acid lowering drugs in cardiovascular diseases. Indeed, clinical studies have reported on the beneficial effects of uric acid lowering drugs, in particular of xanthine oxidase inhibitors, in hypertension, ischemic heart disease and heart failure. Two main mechanisms have been claimed to explain the dangerous effects of hyperuricemia and, as a consequence, the benefits of uric acid lowering therapy: endothelial dysfunction and systemic inflammation. This brief review aims to summarize current evidence from human studies on the role of acid uric lowering therapy in cardiovascular diseases for practical and clinical purposes. The possible mechanisms underlying the benefits of acid uric lowering therapy are also addressed." @default.
• W1141258917 created "2016-06-24" @default.
• W1141258917 creator A5043038293 @default.
• W1141258917 creator A5052136656 @default.
• W1141258917 creator A5059131786 @default.
• W1141258917 creator A5066862358 @default.
• W1141258917 date "2016-06-01" @default.
• W1141258917 modified "2023-10-14" @default.
• W1141258917 title "Uric acid lowering therapy in cardiovascular diseases" @default.
• W1141258917 cites W1414418298 @default.
• W1141258917 cites W1748602285 @default.
• W1141258917 cites W1757751439 @default.
• W1141258917 cites W1953423403 @default.
• W1141258917 cites W1963805301 @default.
• W1141258917 cites W1965503220 @default.
• W1141258917 cites W1977110551 @default.
• W1141258917 cites W1978526436 @default.
• W1141258917 cites W1978747078 @default.
• W1141258917 cites W1981111193 @default.
• W1141258917 cites W1999869967 @default.
• W1141258917 cites W2001592623 @default.
• W1141258917 cites W2020714609 @default.
• W1141258917 cites W2022503135 @default.
• W1141258917 cites W2031005241 @default.
• W1141258917 cites W2043031422 @default.
• W1141258917 cites W2043172105 @default.
• W1141258917 cites W2048477303 @default.
• W1141258917 cites W2054392576 @default.
• W1141258917 cites W2056045638 @default.
• W1141258917 cites W2065408606 @default.
• W1141258917 cites W2066843609 @default.
• W1141258917 cites W2069889029 @default.
• W1141258917 cites W2095535221 @default.
• W1141258917 cites W2096521438 @default.
• W1141258917 cites W2099120495 @default.
• W1141258917 cites W2099703350 @default.
• W1141258917 cites W2101391992 @default.
• W1141258917 cites W2104948653 @default.
• W1141258917 cites W2105044392 @default.
• W1141258917 cites W2111277253 @default.
• W1141258917 cites W2122347435 @default.
• W1141258917 cites W2123162884 @default.
• W1141258917 cites W2125577212 @default.
• W1141258917 cites W2126654035 @default.
• W1141258917 cites W2129194977 @default.
• W1141258917 cites W2132895884 @default.
• W1141258917 cites W2137913776 @default.
• W1141258917 cites W2141653683 @default.
• W1141258917 cites W2144308706 @default.
• W1141258917 cites W2145612945 @default.
• W1141258917 cites W2147946942 @default.
• W1141258917 cites W2147978034 @default.
• W1141258917 cites W2148945798 @default.
• W1141258917 cites W2150619497 @default.
• W1141258917 cites W2163333582 @default.
• W1141258917 cites W2164032217 @default.
• W1141258917 cites W2167491049 @default.
• W1141258917 cites W2168816218 @default.
• W1141258917 cites W2172160209 @default.
• W1141258917 cites W2328029521 @default.
• W1141258917 doi "https://doi.org/10.1016/j.ijcard.2015.08.088" @default.
• W1141258917 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26386814" @default.
• W1141258917 hasPublicationYear "2016" @default.
• W1141258917 type Work @default.
• W1141258917 sameAs 1141258917 @default.
• W1141258917 citedByCount "40" @default.
• W1141258917 countsByYear W11412589172016 @default.
• W1141258917 countsByYear W11412589172017 @default.
• W1141258917 countsByYear W11412589172018 @default.
• W1141258917 countsByYear W11412589172019 @default.
• W1141258917 countsByYear W11412589172020 @default.
• W1141258917 countsByYear W11412589172021 @default.
• W1141258917 countsByYear W11412589172022 @default.
• W1141258917 countsByYear W11412589172023 @default.
• W1141258917 crossrefType "journal-article" @default.
• W1141258917 hasAuthorship W1141258917A5043038293 @default.
• W1141258917 hasAuthorship W1141258917A5052136656 @default.
• W1141258917 hasAuthorship W1141258917A5059131786 @default.
• W1141258917 hasAuthorship W1141258917A5066862358 @default.
• W1141258917 hasConcept C126322002 @default.
• W1141258917 hasConcept C164705383 @default.
• W1141258917 hasConcept C177713679 @default.
• W1141258917 hasConcept C181199279 @default.
• W1141258917 hasConcept C185592680 @default.
• W1141258917 hasConcept C2778102346 @default.
• W1141258917 hasConcept C2778198053 @default.
• W1141258917 hasConcept C2779134260 @default.
• W1141258917 hasConcept C2779721657 @default.
• W1141258917 hasConcept C2779881121 @default.
• W1141258917 hasConcept C2780402116 @default.
• W1141258917 hasConcept C2780932893 @default.
• W1141258917 hasConcept C500558357 @default.
• W1141258917 hasConcept C50440223 @default.
• W1141258917 hasConcept C55493867 @default.
• W1141258917 hasConcept C71924100 @default.
• W1141258917 hasConceptScore W1141258917C126322002 @default.
• W1141258917 hasConceptScore W1141258917C164705383 @default.
• W1141258917 hasConceptScore W1141258917C177713679 @default.

• next