Matches in SemOpenAlex for { <https://semopenalex.org/work/W114128214> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W114128214 endingPage "0204" @default.
- W114128214 startingPage "0202" @default.
- W114128214 abstract "We estimated the number of different human genes by relating the patterns of spontaneous mutation at the population and individual level. A geometric distribution model of mutation was used in which the average rates of nucleotide replacement (P) and mutation at a locus (p), obtained by experiment, were used to determine the estimate of the physical size of the coding genome (n) in man. The probabilistic relation used, P = (1 −p) n−1 p, integrates two different referential time scales of mutation, that of a nucleotide and year and that of a coding gene and generation. The estimates of n, for different values of P and p, are compatible with the experimentally determined genome sizes. The size of the coding portion of the genome appears to be evolutionarily constrained by an interplay between the rate of nucleotide replacement and the pattern of mutation at the level of the individual locus. The evolution of the size of the coding genome may be more dependent on the number of generations than on time." @default.
- W114128214 created "2016-06-24" @default.
- W114128214 creator A5005402817 @default.
- W114128214 creator A5048745441 @default.
- W114128214 creator A5058724451 @default.
- W114128214 creator A5071214836 @default.
- W114128214 date "2002-04-01" @default.
- W114128214 modified "2023-10-15" @default.
- W114128214 cites W1545009729 @default.
- W114128214 cites W2015797441 @default.
- W114128214 cites W2021308523 @default.
- W114128214 cites W2021776752 @default.
- W114128214 cites W2037764264 @default.
- W114128214 cites W2045391589 @default.
- W114128214 cites W2048725294 @default.
- W114128214 cites W2053090649 @default.
- W114128214 cites W2063995899 @default.
- W114128214 cites W2126653676 @default.
- W114128214 cites W2127230663 @default.
- W114128214 cites W2149943693 @default.
- W114128214 doi "https://doi.org/10.1007/s100380200024" @default.
- W114128214 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12166657" @default.
- W114128214 hasPublicationYear "2002" @default.
- W114128214 type Work @default.
- W114128214 sameAs 114128214 @default.
- W114128214 citedByCount "0" @default.
- W114128214 crossrefType "journal-article" @default.
- W114128214 hasAuthorship W114128214A5005402817 @default.
- W114128214 hasAuthorship W114128214A5048745441 @default.
- W114128214 hasAuthorship W114128214A5058724451 @default.
- W114128214 hasAuthorship W114128214A5071214836 @default.
- W114128214 hasBestOaLocation W1141282141 @default.
- W114128214 hasConcept C104317684 @default.
- W114128214 hasConcept C141231307 @default.
- W114128214 hasConcept C144024400 @default.
- W114128214 hasConcept C149923435 @default.
- W114128214 hasConcept C2908647359 @default.
- W114128214 hasConcept C54355233 @default.
- W114128214 hasConcept C84597430 @default.
- W114128214 hasConcept C86803240 @default.
- W114128214 hasConcept C98638677 @default.
- W114128214 hasConceptScore W114128214C104317684 @default.
- W114128214 hasConceptScore W114128214C141231307 @default.
- W114128214 hasConceptScore W114128214C144024400 @default.
- W114128214 hasConceptScore W114128214C149923435 @default.
- W114128214 hasConceptScore W114128214C2908647359 @default.
- W114128214 hasConceptScore W114128214C54355233 @default.
- W114128214 hasConceptScore W114128214C84597430 @default.
- W114128214 hasConceptScore W114128214C86803240 @default.
- W114128214 hasConceptScore W114128214C98638677 @default.
- W114128214 hasIssue "4" @default.
- W114128214 hasLocation W1141282141 @default.
- W114128214 hasLocation W1141282142 @default.
- W114128214 hasOpenAccess W114128214 @default.
- W114128214 hasPrimaryLocation W1141282141 @default.
- W114128214 hasRelatedWork W1828691184 @default.
- W114128214 hasRelatedWork W1886625688 @default.
- W114128214 hasRelatedWork W2028087115 @default.
- W114128214 hasRelatedWork W2057739827 @default.
- W114128214 hasRelatedWork W2074557265 @default.
- W114128214 hasRelatedWork W2082080217 @default.
- W114128214 hasRelatedWork W2082451158 @default.
- W114128214 hasRelatedWork W2104498991 @default.
- W114128214 hasRelatedWork W2465559157 @default.
- W114128214 hasRelatedWork W4233150668 @default.
- W114128214 hasVolume "47" @default.
- W114128214 isParatext "false" @default.
- W114128214 isRetracted "false" @default.
- W114128214 magId "114128214" @default.
- W114128214 workType "article" @default.