Matches in SemOpenAlex for { <https://semopenalex.org/work/W114193000> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W114193000 endingPage "302" @default.
- W114193000 startingPage "295" @default.
- W114193000 abstract "The proposed aetiologies of multiple sclerosis (MS) have included immunological mechanisms, genetic factors, virus infection and direct or indirect action of minerals and/or metals. The processes of these aetiologies have implicated magnesium. Magnesium and zinc have been shown to be decreased in central nervous system (CNS) tissues of MS patients, especially tissues such as white matter where pathological changes have been observed. The calcium content of white matter has also been found to be decreased in MS patients. The interactions of minerals and/or metals such as calcium, magnesium, aluminium and zinc have also been evaluated in CNS tissues of experimental animal models. These data suggest that these elements are regulated by pooling of minerals and/or metals in bones. Biological actions of magnesium may affect the maintenance and function of nerve cells as well as the proliferation and synthesis of lymphocytes. A magnesium deficit may induce dysfunction of nerve cells or lymphocytes directly and/or indirectly, and thus magnesium depletion may be implicated in the aetiology of MS. The action of zinc helps to prevent virus infection, and zinc deficiency in CNS tissues of MS patients may also be relevant to its aetiology. Magnesium interacts with other minerals and/or metals such as calcium, zinc and aluminium in biological systems, affecting the immune system and influencing the content of these elements in CNS tissues. Because of these interactions, a magnesium deficit could also be a risk factor in the aetiology of MS." @default.
- W114193000 created "2016-06-24" @default.
- W114193000 creator A5023038220 @default.
- W114193000 creator A5089209757 @default.
- W114193000 date "1992-12-01" @default.
- W114193000 modified "2023-09-23" @default.
- W114193000 title "Experimental and clinical studies on dysregulation of magnesium metabolism and the aetiopathogenesis of multiple sclerosis." @default.
- W114193000 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1296766" @default.
- W114193000 hasPublicationYear "1992" @default.
- W114193000 type Work @default.
- W114193000 sameAs 114193000 @default.
- W114193000 citedByCount "7" @default.
- W114193000 countsByYear W1141930002014 @default.
- W114193000 countsByYear W1141930002023 @default.
- W114193000 crossrefType "journal-article" @default.
- W114193000 hasAuthorship W114193000A5023038220 @default.
- W114193000 hasAuthorship W114193000A5089209757 @default.
- W114193000 hasConcept C126322002 @default.
- W114193000 hasConcept C134018914 @default.
- W114193000 hasConcept C178790620 @default.
- W114193000 hasConcept C185592680 @default.
- W114193000 hasConcept C203014093 @default.
- W114193000 hasConcept C2780640218 @default.
- W114193000 hasConcept C519063684 @default.
- W114193000 hasConcept C529278444 @default.
- W114193000 hasConcept C535196362 @default.
- W114193000 hasConcept C543218039 @default.
- W114193000 hasConcept C71924100 @default.
- W114193000 hasConcept C86803240 @default.
- W114193000 hasConcept C8891405 @default.
- W114193000 hasConceptScore W114193000C126322002 @default.
- W114193000 hasConceptScore W114193000C134018914 @default.
- W114193000 hasConceptScore W114193000C178790620 @default.
- W114193000 hasConceptScore W114193000C185592680 @default.
- W114193000 hasConceptScore W114193000C203014093 @default.
- W114193000 hasConceptScore W114193000C2780640218 @default.
- W114193000 hasConceptScore W114193000C519063684 @default.
- W114193000 hasConceptScore W114193000C529278444 @default.
- W114193000 hasConceptScore W114193000C535196362 @default.
- W114193000 hasConceptScore W114193000C543218039 @default.
- W114193000 hasConceptScore W114193000C71924100 @default.
- W114193000 hasConceptScore W114193000C86803240 @default.
- W114193000 hasConceptScore W114193000C8891405 @default.
- W114193000 hasIssue "4" @default.
- W114193000 hasLocation W1141930001 @default.
- W114193000 hasOpenAccess W114193000 @default.
- W114193000 hasPrimaryLocation W1141930001 @default.
- W114193000 hasRelatedWork W1982838468 @default.
- W114193000 hasRelatedWork W2004636024 @default.
- W114193000 hasRelatedWork W2008685496 @default.
- W114193000 hasRelatedWork W2076871704 @default.
- W114193000 hasRelatedWork W2077262359 @default.
- W114193000 hasRelatedWork W2144808653 @default.
- W114193000 hasRelatedWork W2354559196 @default.
- W114193000 hasRelatedWork W2368047222 @default.
- W114193000 hasRelatedWork W2386162304 @default.
- W114193000 hasRelatedWork W2416168032 @default.
- W114193000 hasVolume "5" @default.
- W114193000 isParatext "false" @default.
- W114193000 isRetracted "false" @default.
- W114193000 magId "114193000" @default.
- W114193000 workType "article" @default.