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- W1143128073 abstract "Objective To detect anti-M2 autoantibody using recombinant BCOADC-E2-OGDC-E2 (BO). Methods We purified recombinant BO by Ni-NTA affinity chromatography column and established immune blotting test (IBT) and enzyme-linked immunoadsorbent assay (ELISA) to detect anti-M2 autoantibody in the sera of patients with primary biliary cirrhosis (PBC) which was then compared with that of healthy group and those with other liver diseases or other autoinimune diseases. Results Among the 56 sera from PBC patients, 42 were positive, while all the controls were negative. The positive rate was 75.0% Conclusion The recombinant BO can be used to detect anti-M2 autoantibody specifically and sensitively, which is helpful for the diagnosis of PBC." @default.
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- W1143128073 date "2007-04-01" @default.
- W1143128073 modified "2023-09-27" @default.
- W1143128073 title "OGDC-E2和BCOADA-E2的二联体检测在原发性胆汁性肝硬化中的意义" @default.
- W1143128073 hasPublicationYear "2007" @default.
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