FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W114569884> ?p ?o ?g. }

• W114569884 endingPage "9" @default.
• W114569884 startingPage "111" @default.
• W114569884 abstract "Factors that interfere with the acetylcholine signaling system have long been implicated in cataract. The authors sought to investigate the nature of the electrical response of the intact rabbit lens to acetylcholine.Membrane potential (Vm) and electrical conductance (Gm) were monitored in the isolated, perifused lens by a technique utilizing two internal microelectrodes.Acetylcholine (100 nM to 1 mM) induced a decrease in membrane conductance and a depolarization of membrane potential in the intact lens. The responses were reversed by application of the muscarinic antagonist, atropine (1 microM to 100 microM). In the presence of 1 microM thapsigargin and 30 microM cyclopiazonic acid, acetylcholine still induced an electrical response. Long exposures to acetylcholine induced sustained oscillations of Vm in 10 of 29 lenses (34%). Oscillations were blocked by atropine and the L-type Ca2+ channel blocker nifedipine (10 microM) but were potentiated by thapsigargin.The rabbit lens expressed muscarinic receptors that when activated modulate ionic conductances and cause membrane potential oscillations throughout the tissue. Ca2+ influx rather than primary release from intracellular stores appeared to play a major role in the oscillatory response to acetylcholine." @default.
• W114569884 created "2016-06-24" @default.
• W114569884 creator A5002463730 @default.
• W114569884 creator A5046252066 @default.
• W114569884 creator A5066980464 @default.
• W114569884 date "1998-01-01" @default.
• W114569884 modified "2023-09-23" @default.
• W114569884 title "Acetylcholine-induced membrane potential oscillations in the intact lens." @default.
• W114569884 cites W133221774 @default.
• W114569884 cites W1593405189 @default.
• W114569884 cites W1665071864 @default.
• W114569884 cites W180488675 @default.
• W114569884 cites W1965472751 @default.
• W114569884 cites W1965922737 @default.
• W114569884 cites W1972467089 @default.
• W114569884 cites W1983423336 @default.
• W114569884 cites W1984636167 @default.
• W114569884 cites W1988648437 @default.
• W114569884 cites W1990674615 @default.
• W114569884 cites W2013506971 @default.
• W114569884 cites W2027704309 @default.
• W114569884 cites W2031879367 @default.
• W114569884 cites W2033713820 @default.
• W114569884 cites W2036923572 @default.
• W114569884 cites W2050996013 @default.
• W114569884 cites W2056283284 @default.
• W114569884 cites W2058837235 @default.
• W114569884 cites W2059690890 @default.
• W114569884 cites W2063450103 @default.
• W114569884 cites W2063535351 @default.
• W114569884 cites W2078509049 @default.
• W114569884 cites W2089991403 @default.
• W114569884 cites W2090184497 @default.
• W114569884 cites W2093507972 @default.
• W114569884 cites W2099612914 @default.
• W114569884 cites W2405193373 @default.
• W114569884 cites W2416305518 @default.
• W114569884 cites W3165054419 @default.
• W114569884 cites W3166029991 @default.
• W114569884 cites W5001976 @default.
• W114569884 cites W1495980955 @default.
• W114569884 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9430552" @default.
• W114569884 hasPublicationYear "1998" @default.
• W114569884 type Work @default.
• W114569884 sameAs 114569884 @default.
• W114569884 citedByCount "7" @default.
• W114569884 crossrefType "journal-article" @default.
• W114569884 hasAuthorship W114569884A5002463730 @default.
• W114569884 hasAuthorship W114569884A5046252066 @default.
• W114569884 hasAuthorship W114569884A5066980464 @default.
• W114569884 hasConcept C116289061 @default.
• W114569884 hasConcept C12554922 @default.
• W114569884 hasConcept C126322002 @default.
• W114569884 hasConcept C134018914 @default.
• W114569884 hasConcept C170493617 @default.
• W114569884 hasConcept C181911157 @default.
• W114569884 hasConcept C185592680 @default.
• W114569884 hasConcept C2775859210 @default.
• W114569884 hasConcept C2775910092 @default.
• W114569884 hasConcept C2777146706 @default.
• W114569884 hasConcept C2778824757 @default.
• W114569884 hasConcept C33789571 @default.
• W114569884 hasConcept C4141045 @default.
• W114569884 hasConcept C55493867 @default.
• W114569884 hasConcept C71924100 @default.
• W114569884 hasConcept C79879829 @default.
• W114569884 hasConcept C80161118 @default.
• W114569884 hasConcept C86803240 @default.
• W114569884 hasConceptScore W114569884C116289061 @default.
• W114569884 hasConceptScore W114569884C12554922 @default.
• W114569884 hasConceptScore W114569884C126322002 @default.
• W114569884 hasConceptScore W114569884C134018914 @default.
• W114569884 hasConceptScore W114569884C170493617 @default.
• W114569884 hasConceptScore W114569884C181911157 @default.
• W114569884 hasConceptScore W114569884C185592680 @default.
• W114569884 hasConceptScore W114569884C2775859210 @default.
• W114569884 hasConceptScore W114569884C2775910092 @default.
• W114569884 hasConceptScore W114569884C2777146706 @default.
• W114569884 hasConceptScore W114569884C2778824757 @default.
• W114569884 hasConceptScore W114569884C33789571 @default.
• W114569884 hasConceptScore W114569884C4141045 @default.
• W114569884 hasConceptScore W114569884C55493867 @default.
• W114569884 hasConceptScore W114569884C71924100 @default.
• W114569884 hasConceptScore W114569884C79879829 @default.
• W114569884 hasConceptScore W114569884C80161118 @default.
• W114569884 hasConceptScore W114569884C86803240 @default.
• W114569884 hasIssue "1" @default.
• W114569884 hasLocation W1145698841 @default.
• W114569884 hasOpenAccess W114569884 @default.
• W114569884 hasPrimaryLocation W1145698841 @default.
• W114569884 hasRelatedWork W114569884 @default.
• W114569884 hasRelatedWork W145652820 @default.
• W114569884 hasRelatedWork W2000618992 @default.
• W114569884 hasRelatedWork W2011822860 @default.
• W114569884 hasRelatedWork W2032653358 @default.
• W114569884 hasRelatedWork W2034380815 @default.
• W114569884 hasRelatedWork W2053351592 @default.
• W114569884 hasRelatedWork W2160953928 @default.

• next