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- W11462192 abstract "The re-alignment of series of medical images in which there are multiple contrast variations is difficult.The reason for this is that the popularmeasures of image similarity used to drive the alignment proceduredo not separate the influence of intensity variation due to image feature motion and intensity variationdue to feature enhancement. In particular, the appearance of new structure poses problems when ithas no representation in the original image. The acquisition of many images over time, such as indynamic contrast enhanced MRI, requires that many images with different contrast be registered to thesame coordinate system, compounding the problem. This thesis addresses these issues, beginning bypresenting conditions under which conventional registration fails and proposing a solution in the form ofa ’progressive principal component registration’. The algorithm uses a statistical analysis of a series ofcontrast varying images in order to reduce the influence of contrast-enhancement that would otherwisedistort the calculation of the image similarity measures used in image registration. The algorithm isshown to be versatile in that it may be applied to series of images in which contrast variation is due toeither temporal contrast enhancement changes, as in dynamic contrast-enhanced MRI or intrinsically inthe image selection procedure as in diffusion weighted MRI." @default.
- W11462192 created "2016-06-24" @default.
- W11462192 creator A5035099926 @default.
- W11462192 date "2009-03-01" @default.
- W11462192 modified "2023-09-23" @default.
- W11462192 title "Alignment of contrast enhanced medical images" @default.
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