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- W1148618837 abstract "Although the incidence of caries worldwide has declined in recent years, it is necessary to search for new means to overcome this disease and its microbiological agents. Phytochemistry can become an effective alternative to antibiotics, offering a promising strategy in the prevention and therapy of dental caries. This study aimed to evaluate in vitro the bactericide activity of a bioactive phytocomponent from Melia azedarach against Streptococcus mutans. The crude extract (CEx) from leaves and stem barks of M. azedarach in chloroform, petroleum ether, acetate ethyl, butanol, and aqueous fractions was evaluated using seven different concentrations. Disk diffusion and minimum inhibitory concentration assays were used to evaluate the antibacterial activity. 0.12% chlorhexidine was used as a positive control. The CEx and the petroleum ether fraction from M. azedarach showed significant antibacterial activity against S. mutans, confirming its antibiotic potential." @default.
- W1148618837 created "2016-06-24" @default.
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- W1148618837 date "2015-02-01" @default.
- W1148618837 modified "2023-09-25" @default.
- W1148618837 title "Evaluation of Melia azedarach Extracts Against Streptococcus mutans" @default.
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- W1148618837 doi "https://doi.org/10.1089/jmf.2013.0181" @default.
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