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- W115180810 abstract "The objective of this study was to evaluate the contribution of lactic acid bacteria on the urinary and the fecal Trp-P1 (3-amino-1, 4-dimethyl-5H-pyrido [4, 3-b] indole) excretion. Eight weeks old Wister strain male rats were housed in individual cages, in an air-conditioned room where the temperature was maintained at 22°C and Humidity at 50±5% were maintained. The rats were divided into two groups of four each. They were fed ad libitum powdered Oriental rat chow supplemented with 1% w/w or 9% w/w lyophilized Lactobacillus casei subsp. casei R-52 cells (4.1×109 cfu/g)and water. After 4 days of preliminary feeding, 1.0ml of Trp-Pl solution (2.0mg/ml) was infused into the stomach. After 24 hours of Trp-P1 infusion, samples of feces and urine were collected separately for 2 days at 24 hours intervals. Trp-P1 concentration in all the samples were analyzed using HPLC. Administration of the chow supplemented with lyophilized Lactobacillus casei subsp. casei R-52 cells showed no effect on fecal Trp-P1 excretion was observed. However, the concentration of Trp-P1 in the urine was significantly increased by the administration of the chow supplemented with 9% w/w cells (p<0.05), but not with 1% w/w." @default.
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- W115180810 date "1996-01-01" @default.
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- W115180810 title "Effect of Administration of Lactic Acid Bacteria on the Excretion of an Amino Acid Pyrolysate in Rats, Trp-P1 in Feces and Urine" @default.
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- W115180810 doi "https://doi.org/10.2508/chikusan.67.801" @default.
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