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• W115459281 abstract "No AccessJournal of Urology1 Feb 1994Vascular Abnormalities in Peyronie’s Disease: The Role of Color Doppler Sonography Francesco Montorsi, Giorgio Guazzoni, Franco Bergamaschi, Paolo Consonni, Patrizio Rigatti, Giuliano Pizzini, and Alberto Miani Francesco MontorsiFrancesco Montorsi More articles by this author , Giorgio GuazzoniGiorgio Guazzoni More articles by this author , Franco BergamaschiFranco Bergamaschi More articles by this author , Paolo ConsonniPaolo Consonni More articles by this author , Patrizio RigattiPatrizio Rigatti More articles by this author , Giuliano PizziniGiuliano Pizzini More articles by this author , and Alberto MianiAlberto Miani More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)34952-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail We attempted to clarify the role of color Doppler sonography in assessing the vascular function of untreated Peyronie’s disease. A total of 50 patients with a mean 20-month history of penile curvature underwent color Doppler sonography with the penis in the flaccid state and after intracavernous injection of 20μg. prostaglandin El. Of the patients 41 (82%) complained of various degrees of erectile dysfunction, while 9 (18%) reported sustained rigid erections. Pathological peak systolic flow velocities (less than 30cm. per second) of the cavernous arteries were found bilaterally in 10 patients (20%) and unilaterally in 10 (20%). Peak systolic flow velocity correlated positively with cavernous artery flow volume and with acceleration. Cavernous artery end diastolic velocity and resistance index, measured 15 and 30minutes after vasoactive injection and genital manipulation, were indicative of corporeal veno-occlusive dysfunction (greater than 10 and less than 0.75cm. per second, respectively) in 32 patients (65%). Of these patients, 11 (22%) had mixed arteriovenous dysfunction and 9 (18%) had normal cavernous artery flow velocities. Flow along the cavernous arteries is sometimes altered in cases of Peyronie’s disease while corporeal veno-occlusive dysfunction seems to be the main hemodynamic abnormality. Color Doppler sonography should be considered as the initial step in the diagnostic evaluation of patients with Peyronie’s disease who may be eligible for surgical treatment. References 1. : Peyronie’s disease and impotence. Acta Urol. Belg.1988; 56: 317. Google Scholar 2. : The diagnosis and management of Peyronie’s disease. Int. J. Impot. Res.1991; 3: 69. Google Scholar 3. : Penile implants in the treatment of Peyronie’s disease. J. Urol.1991; 145: 69. Link, Google Scholar 4. : Results of surgical management of Peyronie’s disease. J. Urol.1992; 148: 1184. Link, Google Scholar 5. : Surgery of the penis and urethra. chapt. 83 In: . Edited by . Philadelphia: W. B. Saunders Co.1992: 2957. 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Montorsi, F., Bergamaschi, F., Guazzoni, G., Ferini-Strambi, L., Barbieri, L. and Rigatti, P.: Morphodynamic assessment of penile circulation in impotent patients: the role of duplex and color Doppler sonography. Scand. J. Urol. Nephrol., in press. Google Scholar 22. : Physiology of erection and pharmacological management of impotence. J. Urol.1987; 137: 829. Link, Google Scholar 23. : Duplex and color Doppler sonographic evaluation of vasculogenic impotence. AJR1989; 153: 1141. Google Scholar 24. : The combined intracavernous injection and stimulation test: diagnostic accuracy. J. Urol.1992; 148: 61. Link, Google Scholar 25. : Diagnosis and therapy of erectile dysfunction. chapt. 84 In: . Edited by . Philadelphia: W. B. Saunders Co1992: 3033. Google Scholar © 1994 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited BySafarinejad M, Shafiei N and Safarinejad S (2018) The Influence of Promoter –202 A/C Polymorphism (rs2854744) of the IGFBP-3 Gene on Erectile Dysfunction Risk and Serum Levels of IGF-I and IGFBP-3Journal of Urology, VOL. 189, NO. 1, (374-379), Online publication date: 1-Jan-2013.Deveci S, Palese M, Parker M, Guhring P and Mulhall J (2018) Erectile Function Profiles in Men With Peyronie’s DiseaseJournal of Urology, VOL. 175, NO. 5, (1807-1811), Online publication date: 1-May-2006.KENDIRCI M, NOWFAR S, GUR S, JABREN G, SIKKA S and HELLSTROM W (2018) THE RELATIONSHIP BETWEEN THE TYPE OF PENILE ABNORMALITY AND PENILE VASCULAR STATUS IN PATIENTS WITH PEYRONIE'S DISEASEJournal of Urology, VOL. 174, NO. 2, (632-635), Online publication date: 1-Aug-2005.USTA M, BIVALACQUA T, TOKATLI Z, RIVERA F, GULKESEN K, SIKKA S and HELLSTROM W (2018) STRATIFICATION OF PENILE VASCULAR PATHOLOGIES IN PATIENTS WITH PEYRONIE’S DISEASE AND IN MEN WITH ERECTILE DYSFUNCTION ACCORDING TO AGE: A COMPARATIVE STUDYJournal of Urology, VOL. 172, NO. 1, (259-262), Online publication date: 1-Jul-2004.YURKANIN J, DEAN R and WESSELLS H (2018) EFFECT OF INCISION AND SAPHENOUS VEIN GRAFTING FOR PEYRONIE’S DISEASE ON PENILE LENGTH AND SEXUAL SATISFACTIONJournal of Urology, VOL. 166, NO. 5, (1769-1773), Online publication date: 1-Nov-2001.TELOKEN C, RHODEN E, GRAZZIOTIN T, DA ROS C, SOGARI P and SOUTO C (2018) TAMOXIFEN VERSUS PLACEBO IN THE TREATMENT OF PEYRONIE’S DISEASEJournal of Urology, VOL. 162, NO. 6, (2003-2005), Online publication date: 1-Dec-1999.EL-SAKKA A, RASHWAN H and LUE T (2018) VENOUS PATCH GRAFT FOR PEYRONIE'S DISEASE. PART II: OUTCOME ANALYSISJournal of Urology, VOL. 160, NO. 6 Part 1, (2050-2053), Online publication date: 1-Dec-1998.Weidner W, Schroeder-Printzen I, Weiske W and Vosshenrich R (2018) Sexual Dysfunction in Peyronie's Disease: An Analysis of 222 Patients Without Previous Local Plaque TherapyJournal of Urology, VOL. 157, NO. 1, (325-328), Online publication date: 1-Jan-1997.Ganabathi K, Dmochowski R, Zimmern P and Leach G (2018) Peyronie's Disease: Surgical Treatment Based on Penile RigidityJournal of Urology, VOL. 153, NO. 3, (662-666), Online publication date: 1-Mar-1995. Volume 151Issue 2February 1994Page: 373-375 Advertisement Copyright & Permissions© 1994 by The American Urological Association Education and Research, Inc.KeywordsultrasonographyDoppler ultrasoundpenile indurationpenisMetricsAuthor Information Francesco Montorsi More articles by this author Giorgio Guazzoni More articles by this author Franco Bergamaschi More articles by this author Paolo Consonni More articles by this author Patrizio Rigatti More articles by this author Giuliano Pizzini More articles by this author Alberto Miani More articles by this author Expand All Advertisement Loading ..." @default.
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