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- W1155390618 abstract "Publisher Summary This chapter reviews the method of assaying cellular transferrin receptors by measuring the binding of 125 I-labeled diferric transferrin to cells. Transferrin receptors can be measured on cultured cells with either radiolabeled transferrin or with specific antireceptor antibodies. Diferric transferrin binds to specific receptors present on the surface of maturing erythroid cells and a variety of other cultured cell lines. The diferric transferrin–transferrin receptor complex is internalized into an acidic, membranebound, and nonlysosomal compartment (the endosome) where iron is released. At the acidic pH of the endosome, apotransferrin remains bound to the receptor and the apotransferrin–transferrin receptor complex is recycled to the cell surface." @default.
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- W1155390618 date "1987-01-01" @default.
- W1155390618 modified "2023-09-27" @default.
- W1155390618 title "[22] Receptor assay with radiolabeled transferrin" @default.
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- W1155390618 doi "https://doi.org/10.1016/0076-6879(87)47115-2" @default.
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