FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W115576369> ?p ?o ?g. }

• W115576369 endingPage "1459" @default.
• W115576369 startingPage "1453" @default.
• W115576369 abstract "Rationale and Objectives This study examined the value of intraoperative specimen radiography (SR) in determining margin status of excised breast lesions. Of interest was the concordance between the radiologic and histopathologic interpretation of margins. We investigated the influence of in situ disease and of one versus two radiologic views on this concordance. Materials and Methods Our study consisted of 112 women who underwent breast conservation therapy (BCT) during 2002. Margins were examined with one- or two-view SR. Margins were histologically positive if malignant cells resided ≤1 mm from the specimen edge. The McNemar’s test was used to determine concordance between SR and histopathology (HP). Because surgeons excised extra tissue in cases of positive radiologic margins, we believe that a change in margin status occurred in which true positives became false positives. Accordingly, we analyzed our data with multiple iterations in which, one by one, false positives were considered true positives. Results Concordance between SR and HP reached statistical significance after 5/17 false positives were considered true positives. Data excluding DCIS reached significance after 6 of 6 false positives were considered true positives. One- and two-view SR reached significance when 2 of 8 and 7 of 9 false positives, respectively, were considered true positives. Conclusion In conclusion, our study suggests that SR can aid in margin assessment for patients undergoing BCT. We did not find that concordance between SR and HP is higher in cases of purely invasive disease. Concordance was higher in one-view SR in comparison to two-view. A larger sample size should be analyzed before recommending against using two views. This study examined the value of intraoperative specimen radiography (SR) in determining margin status of excised breast lesions. Of interest was the concordance between the radiologic and histopathologic interpretation of margins. We investigated the influence of in situ disease and of one versus two radiologic views on this concordance. Our study consisted of 112 women who underwent breast conservation therapy (BCT) during 2002. Margins were examined with one- or two-view SR. Margins were histologically positive if malignant cells resided ≤1 mm from the specimen edge. The McNemar’s test was used to determine concordance between SR and histopathology (HP). Because surgeons excised extra tissue in cases of positive radiologic margins, we believe that a change in margin status occurred in which true positives became false positives. Accordingly, we analyzed our data with multiple iterations in which, one by one, false positives were considered true positives. Concordance between SR and HP reached statistical significance after 5/17 false positives were considered true positives. Data excluding DCIS reached significance after 6 of 6 false positives were considered true positives. One- and two-view SR reached significance when 2 of 8 and 7 of 9 false positives, respectively, were considered true positives. In conclusion, our study suggests that SR can aid in margin assessment for patients undergoing BCT. We did not find that concordance between SR and HP is higher in cases of purely invasive disease. Concordance was higher in one-view SR in comparison to two-view. A larger sample size should be analyzed before recommending against using two views." @default.
• W115576369 created "2016-06-24" @default.
• W115576369 creator A5023736611 @default.
• W115576369 creator A5033672192 @default.
• W115576369 creator A5059824722 @default.
• W115576369 date "2006-12-01" @default.
• W115576369 modified "2023-09-26" @default.
• W115576369 title "Breast Specimen Radiography" @default.
• W115576369 cites W1996422677 @default.
• W115576369 cites W2000576391 @default.
• W115576369 cites W2003932911 @default.
• W115576369 cites W2005301907 @default.
• W115576369 cites W2009919716 @default.
• W115576369 cites W2010397777 @default.
• W115576369 cites W2010871781 @default.
• W115576369 cites W2014651669 @default.
• W115576369 cites W2019972414 @default.
• W115576369 cites W2035176234 @default.
• W115576369 cites W2036807885 @default.
• W115576369 cites W2040236736 @default.
• W115576369 cites W2067420088 @default.
• W115576369 cites W2070246141 @default.
• W115576369 cites W2077400971 @default.
• W115576369 cites W2107640958 @default.
• W115576369 cites W2130746306 @default.
• W115576369 cites W2145250302 @default.
• W115576369 cites W2226378258 @default.
• W115576369 cites W4232682256 @default.
• W115576369 cites W4254981757 @default.
• W115576369 doi "https://doi.org/10.1016/j.acra.2006.08.017" @default.
• W115576369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17138112" @default.
• W115576369 hasPublicationYear "2006" @default.
• W115576369 type Work @default.
• W115576369 sameAs 115576369 @default.
• W115576369 citedByCount "25" @default.
• W115576369 countsByYear W1155763692012 @default.
• W115576369 countsByYear W1155763692013 @default.
• W115576369 countsByYear W1155763692014 @default.
• W115576369 countsByYear W1155763692015 @default.
• W115576369 countsByYear W1155763692016 @default.
• W115576369 countsByYear W1155763692017 @default.
• W115576369 countsByYear W1155763692018 @default.
• W115576369 countsByYear W1155763692019 @default.
• W115576369 countsByYear W1155763692020 @default.
• W115576369 countsByYear W1155763692021 @default.
• W115576369 countsByYear W1155763692022 @default.
• W115576369 crossrefType "journal-article" @default.
• W115576369 hasAuthorship W115576369A5023736611 @default.
• W115576369 hasAuthorship W115576369A5033672192 @default.
• W115576369 hasAuthorship W115576369A5059824722 @default.
• W115576369 hasConcept C105795698 @default.
• W115576369 hasConcept C119857082 @default.
• W115576369 hasConcept C126322002 @default.
• W115576369 hasConcept C126838900 @default.
• W115576369 hasConcept C142724271 @default.
• W115576369 hasConcept C160798450 @default.
• W115576369 hasConcept C186282968 @default.
• W115576369 hasConcept C2989005 @default.
• W115576369 hasConcept C33923547 @default.
• W115576369 hasConcept C36454342 @default.
• W115576369 hasConcept C41008148 @default.
• W115576369 hasConcept C63363279 @default.
• W115576369 hasConcept C64869954 @default.
• W115576369 hasConcept C65409693 @default.
• W115576369 hasConcept C71924100 @default.
• W115576369 hasConcept C774472 @default.
• W115576369 hasConceptScore W115576369C105795698 @default.
• W115576369 hasConceptScore W115576369C119857082 @default.
• W115576369 hasConceptScore W115576369C126322002 @default.
• W115576369 hasConceptScore W115576369C126838900 @default.
• W115576369 hasConceptScore W115576369C142724271 @default.
• W115576369 hasConceptScore W115576369C160798450 @default.
• W115576369 hasConceptScore W115576369C186282968 @default.
• W115576369 hasConceptScore W115576369C2989005 @default.
• W115576369 hasConceptScore W115576369C33923547 @default.
• W115576369 hasConceptScore W115576369C36454342 @default.
• W115576369 hasConceptScore W115576369C41008148 @default.
• W115576369 hasConceptScore W115576369C63363279 @default.
• W115576369 hasConceptScore W115576369C64869954 @default.
• W115576369 hasConceptScore W115576369C65409693 @default.
• W115576369 hasConceptScore W115576369C71924100 @default.
• W115576369 hasConceptScore W115576369C774472 @default.
• W115576369 hasIssue "12" @default.
• W115576369 hasLocation W1155763691 @default.
• W115576369 hasLocation W1155763692 @default.
• W115576369 hasOpenAccess W115576369 @default.
• W115576369 hasPrimaryLocation W1155763691 @default.
• W115576369 hasRelatedWork W109571580 @default.
• W115576369 hasRelatedWork W115576369 @default.
• W115576369 hasRelatedWork W1983023614 @default.
• W115576369 hasRelatedWork W2113414444 @default.
• W115576369 hasRelatedWork W2377483921 @default.
• W115576369 hasRelatedWork W3011622955 @default.
• W115576369 hasRelatedWork W3097438653 @default.
• W115576369 hasRelatedWork W3136307402 @default.
• W115576369 hasRelatedWork W3213726327 @default.
• W115576369 hasRelatedWork W4383187102 @default.
• W115576369 hasVolume "13" @default.

• next