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- W115744991 abstract "Starting with properly collected, processed, annotated, and stored human specimens is critical for successful research using unsupervised, high-throughput technologies for discovery, validation, and translation from such samples. Samples that are not reproducibly collected and managed undermine data generated in platforms, such as mass spectroscopy–based proteomic technologies. The key factors that determine quality of human biosamples are use of consistent methodologies for collection, handling, processing, and storing specimens; understanding the potential sources of bias; and thoroughly annotating the life-cycle of the specimen. These factors apply when a new biospecimen resource is being created or when previously collected or banked samples are being used. Standard operating procedures permit control of bias and ensure that high-quality biosamples result in reproducible data. Compliance with increasingly complex human subject protection regulations governing the collection, management, storage, sharing, and use of human biosamples is essential to ensure that data will be published in high-quality journals, that intellectual property is protected, and that data generated using biosamples can be used as part of submissions to governmental regulatory bodies for product approvals." @default.
- W115744991 created "2016-06-24" @default.
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- W115744991 date "2013-01-01" @default.
- W115744991 modified "2023-10-17" @default.
- W115744991 title "Serum and Plasma Collection" @default.
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- W115744991 doi "https://doi.org/10.1016/b978-0-12-394446-7.00005-4" @default.
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