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• W11589904 startingPage "211" @default.
• W11589904 abstract "In 1941 Huggins and Hodges published for the first time the favorable effects of surgical castration and estrogen treatment on the progression of metastatic prostate cancer. However, this hormonal therapy is not without side effects. Since this pioneering milestone in history of prostate cancer, a further tremendous innovation did not take place. Today, due to intensive clinical, biochemical, nuclear-biological and molecular- biological research, many hormone active treatment variations are available. Besides traditional hormonal therapy, surgical or chemical castration, maximal androgen blockade, nontraditional forms of hormonal therapy, intermittent hormonal therapy, antiandrogens, 5-α-reductase inhibitors, and their combinations, we discuss options toward creating an increased number of side effect-oriented offers of hormonal treatment options, guaranteeing a longer and more comfortable exhaustion of the individual hormonal period of response and probably a longer survival. The prerequisite is a closer-than-ever monitoring by tumor marker and an early observation of symptomatic changes." @default.
• W11589904 created "2016-06-24" @default.
• W11589904 creator A5055429067 @default.
• W11589904 creator A5088495569 @default.
• W11589904 creator A5091697271 @default.
• W11589904 date "2007-06-04" @default.
• W11589904 modified "2023-10-11" @default.
• W11589904 title "The Role of Hormonal Treatment in Prostate Cancer" @default.
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