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- W115979162 abstract "Twenty-six cases of a spottedfever-like illness have been identified on Flinders Island, Tasmania, over a 17 year period. These patients and 335 healthy persons from the island were investigated serologically using the Weil-Felix agglutination test (Proteus sp. antigens OX2, OX19, OXK) and rickettsia-specific microimmunofluorescence. The antigens used in these latter tests comprised one member of the typhus group (Rickettsia typhi) and three membersof the spotted fever group (Rickettsia rickettsII, Rickettsia australis and Rickettsia conoril). Patients with Flinders Island spotted fever showed a higher prevalence of positive reactions to the Weil-Felix tests (with OX2 and OX19 antigens) and a higher prevalence of positive results to rickettsia-specific serological tests (with the exception of antibodies to Rickettsia typhi) than did healthy persons;OX2(36%v. 1%); OX19 (36% v. 1%); Rickettsia rickettsii(42%v. 1%);Rickettsiaaustralis (46%v.1%); Rickettsia conoril (42% v. 1%); Rickettsia typhi (4% v. 4%). In seven of the 26 patients(27%)seroconversion was demonstrated by meansof Weil-Felix tests, confirming recent infection. In six of these patients seroconversion was also demonstrated in rickettsiaspecifictests. Although these results support the clinical evidence that the illness on Flinders Island is caused by a rickettsia of the spotted fever group, the aetiological agent remains to be Isolated." @default.
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- W115979162 date "1991-01-01" @default.
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- W115979162 title "Flinders Island spotted fever: a newly recognised endemic focus of tick typhus in Bass Strait: Part 2. Serological investigations" @default.
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- W115979162 doi "https://doi.org/10.5694/j.1326-5377.1991.tb120994.x" @default.
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