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• W1159895730 abstract "Immunohistochemistry (IHC), also known as immunocytochemistry, refers to the process of detecting antigens (which may be protein or lipid) by exploiting the principle of antibodies binding specifically to antigens in histological and cytological preparations. IHC staining methods which could be by direct or indirect staining are based on immunofluorescence, immunoenzymologic staining or affinity histochemistry in relation to different biotin conjugated with antibodies. This technique which microscopically detects cellular constituents through antibodies of varying specificity has remodeled the domain of diagnostic pathology by hijacking the spotlight on the yet indispensible hematoxylin and eosin (H&E) technique. However, as with any other technique, the use of control samples is critical in accurate interpretation of IHC results for genetic and therapeutic procedures. The multi-staining, antigen retrieval and scoring techniques have further demonstrated the inestimable value of IHC in uncovering, classifying and/or identifying lesions which have earlier proved to be diagnostically elusive. Yet, more researches are still required in the area of its standardization for proper application in routine and clinical investigations in the face of overwhelming emerging diseases." @default.
• W1159895730 created "2016-06-24" @default.
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• W1159895730 date "2015-01-01" @default.
• W1159895730 modified "2023-09-27" @default.
• W1159895730 title "Immunohistochemistry: A Revolutionary Technique in Laboratory Medicine" @default.
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