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- W1163309045 abstract "In recent years, high-resolution microscopy using structured illumination has been practically applied for fluorescent bio-imaging. However, there is a large amount of speckle noise in reflected- and scattered-light images, because structured illumination is typically generated by laser-beam interference. Hence, this high-resolution imaging technique cannot be effectively used in industrial applications. In this study, we attempted to generate structured illumination using two-beam interference of low-coherence light for high-resolution and low-speckle imaging. First, we constructed an optical system consisting of a Michelson interferometer configured in such a manner that it achieved zero optical path-length difference and allowed the interference fringes to be manipulated. Then, we confirmed that the generated structured illumination width corresponded to the coherence length of the light source. As a final result of the resolution improvement experiment, the narrow sample pitch of 0.4 μm was successfully resolved beyond the diffraction limit of 0.74 μm with relatively less speckle noise." @default.
- W1163309045 created "2016-06-24" @default.
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- W1163309045 date "2016-01-01" @default.
- W1163309045 modified "2023-10-12" @default.
- W1163309045 title "Optical microscopy with improved resolution using two-beam interference of low-coherence light" @default.
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- W1163309045 doi "https://doi.org/10.1016/j.measurement.2015.08.016" @default.
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