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- W116663721 endingPage "161" @default.
- W116663721 startingPage "141" @default.
- W116663721 abstract "The brain contains both major subtypes of angiotensin receptors, the angiotensin type 1 (AT1) and angiotensin type 2 (AT2) receptors. This chapter begin s with a review of the distribution of these receptor subtypes in the brain and continues with a discussion of their physiological and behavioral functions, from which it is clear that the AT l and AT2 recepto rs mediate very different centr al actions of angiotensin II (Ang II). However, the primary focus of this chapter is a discussion of the mechanisms through which Ang II, acting via AT1 and AT2 receptors, can produce rapid alterations in neuronal activity and ultimately functional changes. Hence, we review the studies that have demonstrated electrophysiological actions of Ang II in the brain, and then focus on the specific intr acellular signaling molecules that link the angio tensin receptor subtypes to changes in the activity of neuronal membrane ionic currents and firing rate. From this discussion it is clear that the intracellular signaling mechanisms that couple AT1 and AT2 receptors to changes in neuronal activity are vastly different. When taking a broader view of Ang II actions in neurons, it is evident that the signaling molecules responsible for regulation of neuronal activity represent only a few of the intracellular pathways that are modulated by this peptide" @default.
- W116663721 created "2016-06-24" @default.
- W116663721 creator A5004651591 @default.
- W116663721 creator A5014934001 @default.
- W116663721 date "2004-01-01" @default.
- W116663721 modified "2023-09-27" @default.
- W116663721 title "Angiotensin Receptor Signaling in the Brain: Ionic Currents and Neuronal Activity" @default.
- W116663721 cites W1561328458 @default.
- W116663721 cites W1563716772 @default.
- W116663721 cites W1761458604 @default.
- W116663721 cites W1811210869 @default.
- W116663721 cites W1851770675 @default.
- W116663721 cites W1924604258 @default.
- W116663721 cites W1964360405 @default.
- W116663721 cites W1965570459 @default.
- W116663721 cites W1967561584 @default.
- W116663721 cites W1968775932 @default.
- W116663721 cites W1968874083 @default.
- W116663721 cites W1974576069 @default.
- W116663721 cites W1974957881 @default.
- W116663721 cites W1975180184 @default.
- W116663721 cites W1977157826 @default.
- W116663721 cites W1979625216 @default.
- W116663721 cites W1985211547 @default.
- W116663721 cites W1985625400 @default.
- W116663721 cites W1985908862 @default.
- W116663721 cites W1988124023 @default.
- W116663721 cites W1990152014 @default.
- W116663721 cites W1990232803 @default.
- W116663721 cites W1990257506 @default.
- W116663721 cites W1995604303 @default.
- W116663721 cites W1997084645 @default.
- W116663721 cites W1997932090 @default.
- W116663721 cites W1999166389 @default.
- W116663721 cites W2000687788 @default.
- W116663721 cites W2006815857 @default.
- W116663721 cites W2007521033 @default.
- W116663721 cites W2007725897 @default.
- W116663721 cites W2008530471 @default.
- W116663721 cites W2009849089 @default.
- W116663721 cites W2013690237 @default.
- W116663721 cites W2017235854 @default.
- W116663721 cites W2017800047 @default.
- W116663721 cites W2018200136 @default.
- W116663721 cites W2018541556 @default.
- W116663721 cites W2019353944 @default.
- W116663721 cites W2026832023 @default.
- W116663721 cites W2028156214 @default.
- W116663721 cites W2029424515 @default.
- W116663721 cites W2029973079 @default.
- W116663721 cites W2030261100 @default.
- W116663721 cites W2031647568 @default.
- W116663721 cites W2032108603 @default.
- W116663721 cites W2036051892 @default.
- W116663721 cites W2036195231 @default.
- W116663721 cites W2038858346 @default.
- W116663721 cites W2041645980 @default.
- W116663721 cites W2043108613 @default.
- W116663721 cites W2044219020 @default.
- W116663721 cites W2047338524 @default.
- W116663721 cites W2048555542 @default.
- W116663721 cites W2049562758 @default.
- W116663721 cites W2049773210 @default.
- W116663721 cites W2049923017 @default.
- W116663721 cites W2053451913 @default.
- W116663721 cites W2053469757 @default.
- W116663721 cites W2054617605 @default.
- W116663721 cites W2054640522 @default.
- W116663721 cites W2057618421 @default.
- W116663721 cites W2063590940 @default.
- W116663721 cites W2063875555 @default.
- W116663721 cites W2064098156 @default.
- W116663721 cites W2070768579 @default.
- W116663721 cites W2080357442 @default.
- W116663721 cites W2080951265 @default.
- W116663721 cites W2081717784 @default.
- W116663721 cites W2082542825 @default.
- W116663721 cites W2083077388 @default.
- W116663721 cites W2085759859 @default.
- W116663721 cites W2087797989 @default.
- W116663721 cites W2089640144 @default.
- W116663721 cites W2090936211 @default.
- W116663721 cites W2091742267 @default.
- W116663721 cites W2092171289 @default.
- W116663721 cites W2092288244 @default.
- W116663721 cites W2094398755 @default.
- W116663721 cites W2102305358 @default.
- W116663721 cites W2103411175 @default.
- W116663721 cites W2105529770 @default.
- W116663721 cites W2107408838 @default.
- W116663721 cites W2114224597 @default.
- W116663721 cites W2125041118 @default.
- W116663721 cites W2133737094 @default.
- W116663721 cites W2142772865 @default.
- W116663721 cites W2151454641 @default.
- W116663721 cites W2172465647 @default.
- W116663721 cites W2182230456 @default.
- W116663721 cites W2248410127 @default.