Matches in SemOpenAlex for { <https://semopenalex.org/work/W1168797266> ?p ?o ?g. }
- W1168797266 endingPage "200" @default.
- W1168797266 startingPage "191" @default.
- W1168797266 abstract "The obesity epidemic afflicts over one third of the United States population. With few therapies available to combat obesity, a greater understanding of the systemic causes of this and other metabolic disorders is needed to develop new, effective treatments. The mammalian intestinal microbiota contributes to metabolic processes in the host. This review summarizes the research demonstrating the interplay of diet, intestinal microbiota and host metabolism. We detail the effects of diet-induced modifications in microbial activity and resultant impact on (1) sensory perception of macronutrients and total energy intake; (2) nutrient absorption, transport and storage; (3) liver and biliary function; (4) immune-mediated signaling related to adipose inflammation; and (5) circadian rhythm. We also discuss therapeutic strategies aimed to modify host-microbe interactions, including prebiotics, probiotics and postbiotics, as well as fecal microbiota transplantation. Elucidating the role of gut microbes in shaping metabolic homeostasis or dysregulation provides greater insight into disease development and a promising avenue for improved treatment of metabolic dysfunction." @default.
- W1168797266 created "2016-06-24" @default.
- W1168797266 creator A5024918929 @default.
- W1168797266 creator A5037917751 @default.
- W1168797266 creator A5046094902 @default.
- W1168797266 creator A5051346334 @default.
- W1168797266 creator A5075502842 @default.
- W1168797266 date "2016-02-01" @default.
- W1168797266 modified "2023-10-12" @default.
- W1168797266 title "Nutritional modulation of gut microbiota — the impact on metabolic disease pathophysiology" @default.
- W1168797266 cites W1528948449 @default.
- W1168797266 cites W1546454129 @default.
- W1168797266 cites W1933219276 @default.
- W1168797266 cites W1964115194 @default.
- W1168797266 cites W1971415551 @default.
- W1168797266 cites W1973902015 @default.
- W1168797266 cites W1979598489 @default.
- W1168797266 cites W1986142882 @default.
- W1168797266 cites W1994366077 @default.
- W1168797266 cites W1997151200 @default.
- W1168797266 cites W1997672049 @default.
- W1168797266 cites W1997801102 @default.
- W1168797266 cites W1999373531 @default.
- W1168797266 cites W2007282158 @default.
- W1168797266 cites W2007489219 @default.
- W1168797266 cites W2008664022 @default.
- W1168797266 cites W2016504230 @default.
- W1168797266 cites W2016539998 @default.
- W1168797266 cites W2016662511 @default.
- W1168797266 cites W2016971083 @default.
- W1168797266 cites W2026528484 @default.
- W1168797266 cites W2032356948 @default.
- W1168797266 cites W2036514157 @default.
- W1168797266 cites W2037648723 @default.
- W1168797266 cites W2038217946 @default.
- W1168797266 cites W2040874707 @default.
- W1168797266 cites W2042074642 @default.
- W1168797266 cites W2046859247 @default.
- W1168797266 cites W2048853985 @default.
- W1168797266 cites W2050846265 @default.
- W1168797266 cites W2051984731 @default.
- W1168797266 cites W2057039181 @default.
- W1168797266 cites W2057411492 @default.
- W1168797266 cites W2060185417 @default.
- W1168797266 cites W2061559910 @default.
- W1168797266 cites W2062068084 @default.
- W1168797266 cites W2066594184 @default.
- W1168797266 cites W2067756762 @default.
- W1168797266 cites W2069354135 @default.
- W1168797266 cites W2073332363 @default.
- W1168797266 cites W2074263634 @default.
- W1168797266 cites W2074949233 @default.
- W1168797266 cites W2082316454 @default.
- W1168797266 cites W2082509173 @default.
- W1168797266 cites W2083279903 @default.
- W1168797266 cites W2088697466 @default.
- W1168797266 cites W2089177264 @default.
- W1168797266 cites W2089691332 @default.
- W1168797266 cites W2095083007 @default.
- W1168797266 cites W2100009870 @default.
- W1168797266 cites W2103385976 @default.
- W1168797266 cites W2104890139 @default.
- W1168797266 cites W2104969697 @default.
- W1168797266 cites W2118744821 @default.
- W1168797266 cites W2123304665 @default.
- W1168797266 cites W2124025733 @default.
- W1168797266 cites W2127813400 @default.
- W1168797266 cites W2129917444 @default.
- W1168797266 cites W2131536322 @default.
- W1168797266 cites W2134897177 @default.
- W1168797266 cites W2135090436 @default.
- W1168797266 cites W2136552678 @default.
- W1168797266 cites W2136708412 @default.
- W1168797266 cites W2136778785 @default.
- W1168797266 cites W2138546203 @default.
- W1168797266 cites W2140233939 @default.
- W1168797266 cites W2140598936 @default.
- W1168797266 cites W2142336938 @default.
- W1168797266 cites W2143210222 @default.
- W1168797266 cites W2144754352 @default.
- W1168797266 cites W2151798187 @default.
- W1168797266 cites W2153908787 @default.
- W1168797266 cites W2157176317 @default.
- W1168797266 cites W2158038591 @default.
- W1168797266 cites W2159185691 @default.
- W1168797266 cites W2161332823 @default.
- W1168797266 cites W2163591544 @default.
- W1168797266 cites W2166562121 @default.
- W1168797266 cites W2167062509 @default.
- W1168797266 cites W2170666048 @default.
- W1168797266 cites W2171016495 @default.
- W1168797266 cites W2309993734 @default.
- W1168797266 cites W2340570492 @default.
- W1168797266 cites W2409627977 @default.
- W1168797266 cites W4252935541 @default.
- W1168797266 cites W81757240 @default.
- W1168797266 doi "https://doi.org/10.1016/j.jnutbio.2015.08.013" @default.
- W1168797266 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4757500" @default.