Matches in SemOpenAlex for { <https://semopenalex.org/work/W117154433> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W117154433 endingPage "174" @default.
- W117154433 startingPage "165" @default.
- W117154433 abstract "ABSTRACT Limiting dilution analyses using human T and B cells from the peripheral blood of individuals recently (2 to 6 weeks) boosted with a combination of diptheria and tetanus toxoids were performed in order to investigate the specificity of T cell help during in . vitro poke-weed mitogen (PWM) stimulation. Limiting dilutions using B cells were first performed in order to determine the number of potential Ig producing B cells of a variety of specificities activated by PWM induced T cell stimulation. The precursor frequency for total IgG production was 1.3 × 10 −3 with approximately 10% of the B cells directed against tetanus toxoid and 3% directed against diptheria toxoid two weeks after boosting. Limiting numbers of irradiated T cells were then added to an excess of B cells and their ability to help IgG anti-tetanus toxoid (Tet-IgG) and IgG anti-diptheria toxoid (Dip-IgG) antibody production were compared. The helper activity for the Tet-IgG did not dilute out in parallel with help for Dip-IgG. Wells were observed at limiting dilutions of added helper T cells which produced only Tet-IgG or Dip-IgG but not both even though sufficient potential specific IgG producing B cells for each antigen were present." @default.
- W117154433 created "2016-06-24" @default.
- W117154433 creator A5008911888 @default.
- W117154433 creator A5035265333 @default.
- W117154433 date "1979-01-01" @default.
- W117154433 modified "2023-09-25" @default.
- W117154433 title "POSSIBLE ANTIGEN SPECIFIC T CELL HELP IN POKEWEED MITOGEN STIMULATED HUMAN PERIPHERAL BLOOD CELL CULTURES" @default.
- W117154433 cites W1503765073 @default.
- W117154433 cites W1551735549 @default.
- W117154433 cites W1976395553 @default.
- W117154433 cites W2019655807 @default.
- W117154433 cites W2048469310 @default.
- W117154433 cites W2081208246 @default.
- W117154433 cites W4313310042 @default.
- W117154433 doi "https://doi.org/10.1016/b978-0-12-069850-9.50022-5" @default.
- W117154433 hasPublicationYear "1979" @default.
- W117154433 type Work @default.
- W117154433 sameAs 117154433 @default.
- W117154433 citedByCount "0" @default.
- W117154433 crossrefType "book-chapter" @default.
- W117154433 hasAuthorship W117154433A5008911888 @default.
- W117154433 hasAuthorship W117154433A5035265333 @default.
- W117154433 hasConcept C132149769 @default.
- W117154433 hasConcept C137061746 @default.
- W117154433 hasConcept C147483822 @default.
- W117154433 hasConcept C1491633281 @default.
- W117154433 hasConcept C202751555 @default.
- W117154433 hasConcept C203014093 @default.
- W117154433 hasConcept C2781005381 @default.
- W117154433 hasConcept C3017910909 @default.
- W117154433 hasConcept C54355233 @default.
- W117154433 hasConcept C62478195 @default.
- W117154433 hasConcept C86803240 @default.
- W117154433 hasConcept C95444343 @default.
- W117154433 hasConceptScore W117154433C132149769 @default.
- W117154433 hasConceptScore W117154433C137061746 @default.
- W117154433 hasConceptScore W117154433C147483822 @default.
- W117154433 hasConceptScore W117154433C1491633281 @default.
- W117154433 hasConceptScore W117154433C202751555 @default.
- W117154433 hasConceptScore W117154433C203014093 @default.
- W117154433 hasConceptScore W117154433C2781005381 @default.
- W117154433 hasConceptScore W117154433C3017910909 @default.
- W117154433 hasConceptScore W117154433C54355233 @default.
- W117154433 hasConceptScore W117154433C62478195 @default.
- W117154433 hasConceptScore W117154433C86803240 @default.
- W117154433 hasConceptScore W117154433C95444343 @default.
- W117154433 hasLocation W1171544331 @default.
- W117154433 hasOpenAccess W117154433 @default.
- W117154433 hasPrimaryLocation W1171544331 @default.
- W117154433 hasRelatedWork W1542762854 @default.
- W117154433 hasRelatedWork W1972400502 @default.
- W117154433 hasRelatedWork W1996179405 @default.
- W117154433 hasRelatedWork W2030790635 @default.
- W117154433 hasRelatedWork W2049667783 @default.
- W117154433 hasRelatedWork W2094335396 @default.
- W117154433 hasRelatedWork W2417783518 @default.
- W117154433 hasRelatedWork W2423694190 @default.
- W117154433 hasRelatedWork W2469217063 @default.
- W117154433 hasRelatedWork W2525569713 @default.
- W117154433 isParatext "false" @default.
- W117154433 isRetracted "false" @default.
- W117154433 magId "117154433" @default.
- W117154433 workType "book-chapter" @default.