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- W117413036 abstract "The idea of using randomized clinical trials to study cancer prevention is relatively new. In fact, to my knowledge, only a few such trials have been completed and only a few dozen such trials are currently underway in the entire world. This situation contrasts sharply with that for cardiovascular disease, where large-scale randomized intervention trials have been used as a method of study for several decades. In this article I want to show how the design of cancer prevention trials depends on our general concept of carcinogenesis and then describe some real trials which are underway or in the planning stages in order to illustrate some special design considerations that arise in these trials. Finally, I will summarize what seem to me to be some of the major differences between treatment and prevention trials." @default.
- W117413036 created "2016-06-24" @default.
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- W117413036 date "1988-01-01" @default.
- W117413036 modified "2023-09-25" @default.
- W117413036 title "The Design of Cancer Prevention Trials" @default.
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- W117413036 doi "https://doi.org/10.1007/978-3-642-83419-6_5" @default.
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